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Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma.
Kristensen NP, Heeke C, Tvingsholm SA, Borch A, Draghi A, Crowther MD, Carri I, Munk KK, Holm JS, Bjerregaard AM, Bentzen AK, Marquard AM, Szallasi Z, McGranahan N, Andersen R, Nielsen M, Jönsson GB, Donia M, Svane IM, Hadrup SR. Kristensen NP, et al. Among authors: nielsen m. J Clin Invest. 2022 Jan 18;132(2):e150535. doi: 10.1172/JCI150535. J Clin Invest. 2022. PMID: 34813506 Free PMC article. Clinical Trial.
MuPeXI: prediction of neo-epitopes from tumor sequencing data.
Bjerregaard AM, Nielsen M, Hadrup SR, Szallasi Z, Eklund AC. Bjerregaard AM, et al. Among authors: nielsen m. Cancer Immunol Immunother. 2017 Sep;66(9):1123-1130. doi: 10.1007/s00262-017-2001-3. Epub 2017 Apr 20. Cancer Immunol Immunother. 2017. PMID: 28429069 Free PMC article.
An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes.
Bjerregaard AM, Nielsen M, Jurtz V, Barra CM, Hadrup SR, Szallasi Z, Eklund AC. Bjerregaard AM, et al. Among authors: nielsen m. Front Immunol. 2017 Nov 15;8:1566. doi: 10.3389/fimmu.2017.01566. eCollection 2017. Front Immunol. 2017. PMID: 29187854 Free PMC article.
T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.
Bentzen AK, Such L, Jensen KK, Marquard AM, Jessen LE, Miller NJ, Church CD, Lyngaa R, Koelle DM, Becker JC, Linnemann C, Schumacher TNM, Marcatili P, Nghiem P, Nielsen M, Hadrup SR. Bentzen AK, et al. Among authors: nielsen m. Nat Biotechnol. 2018 Nov 19:10.1038/nbt.4303. doi: 10.1038/nbt.4303. Online ahead of print. Nat Biotechnol. 2018. PMID: 30451992 Free PMC article.
Immunization With the CSF-470 Vaccine Plus BCG and rhGM-CSF Induced in a Cutaneous Melanoma Patient a TCRβ Repertoire Found at Vaccination Site and Tumor Infiltrating Lymphocytes That Persisted in Blood.
Aris M, Bravo AI, Garcia Alvarez HM, Carri I, Podaza E, Blanco PA, Rotondaro C, Bentivegna S, Nielsen M, Barrio MM, Mordoh J. Aris M, et al. Among authors: nielsen m. Front Immunol. 2019 Sep 18;10:2213. doi: 10.3389/fimmu.2019.02213. eCollection 2019. Front Immunol. 2019. PMID: 31620131 Free PMC article.
Evaluation of T-Cell Responses Against Shared Melanoma Associated Antigens and Predicted Neoantigens in Cutaneous Melanoma Patients Treated With the CSF-470 Allogeneic Cell Vaccine Plus BCG and GM-CSF.
Podaza E, Carri I, Aris M, von Euw E, Bravo AI, Blanco P, Ortiz Wilczyñski JM, Koile D, Yankilevich P, Nielsen M, Mordoh J, Barrio MM. Podaza E, et al. Among authors: nielsen m. Front Immunol. 2020 Jun 5;11:1147. doi: 10.3389/fimmu.2020.01147. eCollection 2020. Front Immunol. 2020. PMID: 32582212 Free PMC article. Clinical Trial.
Rapid Identification of the Tumor-Specific Reactive TIL Repertoire via Combined Detection of CD137, TNF, and IFNγ, Following Recognition of Autologous Tumor-Antigens.
Draghi A, Chamberlain CA, Khan S, Papp K, Lauss M, Soraggi S, Radic HD, Presti M, Harbst K, Gokuldass A, Kverneland A, Nielsen M, Westergaard MCW, Andersen MH, Csabai I, Jönsson G, Szallasi Z, Svane IM, Donia M. Draghi A, et al. Among authors: nielsen m. Front Immunol. 2021 Oct 11;12:705422. doi: 10.3389/fimmu.2021.705422. eCollection 2021. Front Immunol. 2021. PMID: 34707600 Free PMC article.
4,511 results