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The N501Y spike substitution enhances SARS-CoV-2 infection and transmission.
Liu Y, Liu J, Plante KS, Plante JA, Xie X, Zhang X, Ku Z, An Z, Scharton D, Schindewolf C, Widen SG, Menachery VD, Shi PY, Weaver SC. Liu Y, et al. Among authors: weaver sc. Nature. 2022 Feb;602(7896):294-299. doi: 10.1038/s41586-021-04245-0. Epub 2021 Nov 24. Nature. 2022. PMID: 34818667 Free PMC article.
Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein.
Gorchakov R, Wang E, Leal G, Forrester NL, Plante K, Rossi SL, Partidos CD, Adams AP, Seymour RL, Weger J, Borland EM, Sherman MB, Powers AM, Osorio JE, Weaver SC. Gorchakov R, et al. Among authors: weaver sc. J Virol. 2012 Jun;86(11):6084-96. doi: 10.1128/JVI.06449-11. Epub 2012 Mar 28. J Virol. 2012. PMID: 22457519 Free PMC article.
RNA viruses can hijack vertebrate microRNAs to suppress innate immunity.
Trobaugh DW, Gardner CL, Sun C, Haddow AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. Trobaugh DW, et al. Among authors: weaver sc. Nature. 2014 Feb 13;506(7487):245-8. doi: 10.1038/nature12869. Epub 2013 Dec 18. Nature. 2014. PMID: 24352241 Free PMC article.
534 results