de Bruin HG - Search Results

1

Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells.

Kruk DMLW, Wisman M, Noordhoek JA, Nizamoglu M, Jonker MR, de Bruin HG, Arevalo Gomez K, Ten Hacken NHT, Pouwels SD, Heijink IH. Kruk DMLW, et al. Among authors: de bruin hg. Cells. 2021 Oct 23;10(11):2860. doi: 10.3390/cells10112860. Cells. 2021. PMID: 34831082 Free PMC article.

2

Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium.

Hoffmann RF, Jonker MR, Brandenburg SM, de Bruin HG, Ten Hacken NHT, van Oosterhout AJM, Heijink IH. Hoffmann RF, et al. Among authors: de bruin hg. Sci Rep. 2019 Oct 21;9(1):15047. doi: 10.1038/s41598-019-51517-x. Sci Rep. 2019. PMID: 31636329 Free PMC article.

3

Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease.

Heijink IH, de Bruin HG, van den Berge M, Bennink LJ, Brandenburg SM, Gosens R, van Oosterhout AJ, Postma DS. Heijink IH, et al. Among authors: de bruin hg. Thorax. 2013 Aug;68(8):709-16. doi: 10.1136/thoraxjnl-2012-201667. Epub 2013 Jan 31. Thorax. 2013. PMID: 23370438

4

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells.

Hoffmann RF, Zarrintan S, Brandenburg SM, Kol A, de Bruin HG, Jafari S, Dijk F, Kalicharan D, Kelders M, Gosker HR, Ten Hacken NH, van der Want JJ, van Oosterhout AJ, Heijink IH. Hoffmann RF, et al. Among authors: de bruin hg. Respir Res. 2013 Oct 2;14(1):97. doi: 10.1186/1465-9921-14-97. Respir Res. 2013. PMID: 24088173 Free PMC article.

5

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C, Tsitsiou E, Caramori G, Contoli M, Casolari P, Monaco F, Andò F, Speciale G, Kilty I, Chung KF, Papi A, Lindsay MA, Ten Hacken NH, van den Berge M, Timens W, Barnes PJ, van Oosterhout AJ, Adcock IM, Kirkham PA, Heijink IH. Ngkelo A, et al. Among authors: de bruin hg. Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1112-23. doi: 10.1152/ajplung.00077.2015. Epub 2015 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26320152 Free PMC article.

6

Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

Heijink IH, de Bruin HG, Dennebos R, Jonker MR, Noordhoek JA, Brandsma CA, van den Berge M, Postma DS. Heijink IH, et al. Among authors: de bruin hg. Eur Respir J. 2016 Aug;48(2):504-15. doi: 10.1183/13993003.01541-2015. Epub 2016 Apr 28. Eur Respir J. 2016. PMID: 27126693 Free article.

7

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.

Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Boudewijn IM, et al. Among authors: de bruin hg. Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5. Respir Res. 2017. PMID: 29268739 Free PMC article. Clinical Trial.

8

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.

Heijink IH, Pouwels SD, Leijendekker C, de Bruin HG, Zijlstra GJ, van der Vaart H, ten Hacken NH, van Oosterhout AJ, Nawijn MC, van der Toorn M. Heijink IH, et al. Among authors: de bruin hg. Am J Respir Cell Mol Biol. 2015 May;52(5):554-62. doi: 10.1165/rcmb.2013-0505OC. Am J Respir Cell Mol Biol. 2015. PMID: 25192219 Clinical Trial.

9

Inhibition of β-catenin/CBP signalling improves airway epithelial barrier function and suppresses CCL20 release.

Kuchibhotla VNS, Jonker MR, de Bruin HG, Noordhoek JA, Knight DA, Nawijn MC, Heijink IH. Kuchibhotla VNS, et al. Among authors: de bruin hg. Allergy. 2020 Jul;75(7):1786-1789. doi: 10.1111/all.14216. Epub 2020 Feb 24. Allergy. 2020. PMID: 32027380 Free PMC article. No abstract available.

10

A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke.

Oldenburger A, Poppinga WJ, Kos F, de Bruin HG, Rijks WF, Heijink IH, Timens W, Meurs H, Maarsingh H, Schmidt M. Oldenburger A, et al. Among authors: de bruin hg. Am J Physiol Cell Physiol. 2014 Mar 15;306(6):C585-97. doi: 10.1152/ajpcell.00183.2013. Epub 2014 Jan 22. Am J Physiol Cell Physiol. 2014. PMID: 24452374 Free article.

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