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Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: a test-negative, case-control study and a mechanistic study of post-vaccination immune responses.
Thiruvengadam R, Awasthi A, Medigeshi G, Bhattacharya S, Mani S, Sivasubbu S, Shrivastava T, Samal S, Rathna Murugesan D, Koundinya Desiraju B, Kshetrapal P, Pandey R, Scaria V, Kumar Malik P, Taneja J, Binayke A, Vohra T, Zaheer A, Rathore D, Ahmad Khan N, Shaman H, Ahmed S, Kumar R, Deshpande S, Subramani C, Wadhwa N, Gupta N, Pandey AK, Bhattacharya J, Agrawal A, Vrati S, Bhatnagar S, Garg PK; Department of Biotechnology India Consortium for COVID-19 research. Thiruvengadam R, et al. Among authors: mani s. Lancet Infect Dis. 2022 Apr;22(4):473-482. doi: 10.1016/S1473-3099(21)00680-0. Epub 2021 Nov 25. Lancet Infect Dis. 2022. PMID: 34838183 Free PMC article.
Identification of an anti-SARS-CoV-2 receptor-binding domain-directed human monoclonal antibody from a naïve semisynthetic library.
Parray HA, Chiranjivi AK, Asthana S, Yadav N, Shrivastava T, Mani S, Sharma C, Vishwakarma P, Das S, Pindari K, Sinha S, Samal S, Ahmed S, Kumar R. Parray HA, et al. Among authors: mani s. J Biol Chem. 2020 Sep 4;295(36):12814-12821. doi: 10.1074/jbc.AC120.014918. Epub 2020 Jul 29. J Biol Chem. 2020. PMID: 32727845 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro.
Vishwakarma P, Yadav N, Rizvi ZA, Khan NA, Chiranjivi AK, Mani S, Bansal M, Dwivedi P, Shrivastava T, Kumar R, Awasthi A, Ahmed S, Samal S. Vishwakarma P, et al. Among authors: mani s. Front Immunol. 2021 Mar 26;12:613045. doi: 10.3389/fimmu.2021.613045. eCollection 2021. Front Immunol. 2021. PMID: 33841395 Free PMC article.
Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immune Response in a Mouse Model.
Shrivastava T, Singh B, Rizvi ZA, Verma R, Goswami S, Vishwakarma P, Jakhar K, Sonar S, Mani S, Bhattacharyya S, Awasthi A, Surjit M. Shrivastava T, et al. Among authors: mani s. Front Immunol. 2021 May 24;12:641447. doi: 10.3389/fimmu.2021.641447. eCollection 2021. Front Immunol. 2021. PMID: 34108961 Free PMC article.
Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative.
Malladi SK, Patel UR, Rajmani RS, Singh R, Pandey S, Kumar S, Khaleeq S, van Vuren PJ, Riddell S, Goldie S, Gayathri S, Chakraborty D, Kalita P, Pramanick I, Agarwal N, Reddy P, Girish N, Upadhyaya A, Khan MS, Kanjo K, Bhat M, Mani S, Bhattacharyya S, Siddiqui S, Tyagi A, Jha S, Pandey R, Tripathi S, Dutta S, McAuley AJ, Singanallur NB, Vasan SS, Ringe RP, Varadarajan R. Malladi SK, et al. Among authors: mani s. ACS Infect Dis. 2021 Aug 13;7(8):2546-2564. doi: 10.1021/acsinfecdis.1c00276. Epub 2021 Jul 14. ACS Infect Dis. 2021. PMID: 34260218 Free PMC article.
Non-neutralizing SARS CoV-2 directed polyclonal antibodies demonstrate cross-reactivity with the HA glycans of influenza virus.
Murugavelu P, Perween R, Shrivastava T, Singh V, Ahmad Parray H, Singh S, Chiranjivi AK, Thiruvengadam R, Singh S, Yadav N, Jakhar K, Sonar S, Mani S, Bhattacharyya S, Sharma C, Vishwakarma P, Khatri R, Kumar Panchal A, Das S, Ahmed S, Samal S, Kshetrapal P, Bhatnagar S, Luthra K, Kumar R. Murugavelu P, et al. Among authors: mani s. Int Immunopharmacol. 2021 Oct;99:108020. doi: 10.1016/j.intimp.2021.108020. Epub 2021 Jul 29. Int Immunopharmacol. 2021. PMID: 34426117 Free PMC article.
The SARS CoV-2 spike directed non-neutralizing polyclonal antibodies cross-react with Human immunodeficiency virus (HIV-1) gp41.
Perween R, PraveenKumar M, Shrivastava T, Parray HA, Singh V, Singh S, Chiranjivi A, Jakhar K, Sonar S, Tiwari M, Reema, Panchal AK, Sharma C, Rathore DK, Ahamed S, Samal S, Mani S, Bhattacharyya S, Das S, Luthra K, Kumar R. Perween R, et al. Among authors: mani s. Int Immunopharmacol. 2021 Dec;101(Pt B):108187. doi: 10.1016/j.intimp.2021.108187. Epub 2021 Sep 28. Int Immunopharmacol. 2021. PMID: 34649114 Free PMC article.
High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge.
Ujjainiya R, Tyagi A, Sardana V, Naushin S, Bhatheja N, Kumar K, Barman J, Prakash S, Kutum R, Bhaskar AK, Singh P, Chaudhary K, Loomba M, Khanna Y, Walecha C, Ahmed R, Yadav A, Bajaj A, Malik G, Qureshi S, Waghdhare S, Siddiqui S, Trehan KK, Mani M, Dang R, Das P, Dougall P, Mahajan M, Sonar S, Jakhar K, Kumar R, Tiwari M, Mani S, Bhattacharyya S, Budhiraja S, Agrawal A, Dash D, Jha S, Sengupta S. Ujjainiya R, et al. Among authors: mani m, mani s. Nat Commun. 2022 Apr 1;13(1):1726. doi: 10.1038/s41467-022-29404-3. Nat Commun. 2022. PMID: 35365648 Free PMC article.
1,121 results