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Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma.
Schneider MM, Emmenegger M, Xu CK, Condado Morales I, Meisl G, Turelli P, Zografou C, Zimmermann MR, Frey BM, Fiedler S, Denninger V, Jacquat RP, Madrigal L, Ilsley A, Kosmoliaptsis V, Fiegler H, Trono D, Knowles TP, Aguzzi A. Schneider MM, et al. Among authors: xu ck. Life Sci Alliance. 2021 Nov 30;5(2):e202101270. doi: 10.26508/lsa.202101270. Print 2022 Feb. Life Sci Alliance. 2021. PMID: 34848436 Free PMC article.
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.
Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM. Limbocker R, et al. Among authors: xu ck. Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5. Nat Commun. 2019. PMID: 30644384 Free PMC article.
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies.
Linse S, Scheidt T, Bernfur K, Vendruscolo M, Dobson CM, Cohen SIA, Sileikis E, Lundqvist M, Qian F, O'Malley T, Bussiere T, Weinreb PH, Xu CK, Meisl G, Devenish SRA, Knowles TPJ, Hansson O. Linse S, et al. Among authors: xu ck. Nat Struct Mol Biol. 2020 Dec;27(12):1125-1133. doi: 10.1038/s41594-020-0505-6. Epub 2020 Sep 28. Nat Struct Mol Biol. 2020. PMID: 32989305
Interactions of α-synuclein oligomers with lipid membranes.
Musteikytė G, Jayaram AK, Xu CK, Vendruscolo M, Krainer G, Knowles TPJ. Musteikytė G, et al. Among authors: xu ck. Biochim Biophys Acta Biomembr. 2021 Apr 1;1863(4):183536. doi: 10.1016/j.bbamem.2020.183536. Epub 2020 Dec 26. Biochim Biophys Acta Biomembr. 2021. PMID: 33373595 Free article. Review.
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers.
Cataldi R, Chia S, Pisani K, Ruggeri FS, Xu CK, Šneideris T, Perni M, Sarwat S, Joshi P, Kumita JR, Linse S, Habchi J, Knowles TPJ, Mannini B, Dobson CM, Vendruscolo M. Cataldi R, et al. Among authors: xu ck. Commun Biol. 2021 Jan 4;4(1):19. doi: 10.1038/s42003-020-01490-3. Commun Biol. 2021. PMID: 33398040 Free PMC article.
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers.
Cataldi R, Chia S, Pisani K, Ruggeri FS, Xu CK, Šneideris T, Perni M, Sarwat S, Joshi P, Kumita JR, Linse S, Habchi J, Knowles TPJ, Mannini B, Dobson CM, Vendruscolo M. Cataldi R, et al. Among authors: xu ck. Commun Biol. 2021 Jan 26;4(1):154. doi: 10.1038/s42003-021-01680-7. Commun Biol. 2021. PMID: 33500508 Free PMC article. No abstract available.
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.
Pansieri J, Iashchishyn IA, Fakhouri H, Ostojić L, Malisauskas M, Musteikyte G, Smirnovas V, Schneider MM, Scheidt T, Xu CK, Meisl G, Knowles TPJ, Gazit E, Antoine R, Morozova-Roche LA. Pansieri J, et al. Among authors: xu ck. Chem Sci. 2020 Jun 17;11(27):7031-7039. doi: 10.1039/c9sc05905a. Chem Sci. 2020. PMID: 34122996 Free PMC article.
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers.
Limbocker R, Staats R, Chia S, Ruggeri FS, Mannini B, Xu CK, Perni M, Cascella R, Bigi A, Sasser LR, Block NR, Wright AK, Kreiser RP, Custy ET, Meisl G, Errico S, Habchi J, Flagmeier P, Kartanas T, Hollows JE, Nguyen LT, LeForte K, Barbut D, Kumita JR, Cecchi C, Zasloff M, Knowles TPJ, Dobson CM, Chiti F, Vendruscolo M. Limbocker R, et al. Among authors: xu ck. Front Neurosci. 2021 Jun 18;15:680026. doi: 10.3389/fnins.2021.680026. eCollection 2021. Front Neurosci. 2021. PMID: 34220435 Free PMC article.
51 results