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An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Peng Y, Felce SL, Dong D, Penkava F, Mentzer AJ, Yao X, Liu G, Yin Z, Chen JL, Lu Y, Wellington D, Wing PAC, Dominey-Foy DCC, Jin C, Wang W, Hamid MA, Fernandes RA, Wang B, Fries A, Zhuang X, Ashley N, Rostron T, Waugh C, Sopp P, Hublitz P, Beveridge R, Tan TK, Dold C, Kwok AJ, Rich-Griffin C, Dejnirattisa W, Liu C, Kurupati P, Nassiri I, Watson RA, Tong O, Taylor CA, Kumar Sharma P, Sun B, Curion F, Revale S, Garner LC, Jansen K, Ferreira RC, Attar M, Fry JW, Russell RA; COMBAT Consortium; Stauss HJ, James W, Townsend A, Ho LP, Klenerman P, Mongkolsapaya J, Screaton GR, Dendrou C, Sansom SN, Bashford-Rogers R, Chain B, Smith GL, McKeating JA, Fairfax BP, Bowness P, McMichael AJ, Ogg G, Knight JC, Dong T. Peng Y, et al. Among authors: garner lc. Nat Immunol. 2022 Jan;23(1):50-61. doi: 10.1038/s41590-021-01084-z. Epub 2021 Dec 1. Nat Immunol. 2022. PMID: 34853448 Free PMC article.
Expression of lectin-like transcript-1 in human tissues.
Llibre A, Garner L, Partridge A, Freeman GJ, Klenerman P, Willberg CB. Llibre A, et al. F1000Res. 2016 Dec 29;5:2929. doi: 10.12688/f1000research.10009.1. eCollection 2016. F1000Res. 2016. PMID: 28413611 Free PMC article.
Human MAIT Cell Activation In Vitro.
Hagel JP, Garner LC, Bilton M, Mehta H, Leng T, Hackstein CP, Phalora P, Amini A, Akther HD, Provine NM, Edmans M, Willberg CB, Klenerman P. Hagel JP, et al. Among authors: garner lc. Methods Mol Biol. 2020;2098:97-124. doi: 10.1007/978-1-0716-0207-2_7. Methods Mol Biol. 2020. PMID: 31792818
Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis.
Slevin SM, Garner LC, Lahiff C, Tan M, Wang LM, Ferry H, Greenaway B, Lynch K, Geremia A, Hughes S, Leavens K, Krull D, Marks DJB, Nevin K, Page K, Srinivasan N, Tarzi R, Klenerman P, Travis S, Arancibia-Cárcamo CV, Keshav S. Slevin SM, et al. Among authors: garner lc. J Crohns Colitis. 2020 Oct 5;14(10):1446-1461. doi: 10.1093/ecco-jcc/jjaa054. J Crohns Colitis. 2020. PMID: 32179884 Free PMC article.
MAIT cell activation augments adenovirus vector vaccine immunogenicity.
Provine NM, Amini A, Garner LC, Spencer AJ, Dold C, Hutchings C, Silva Reyes L, FitzPatrick MEB, Chinnakannan S, Oguti B, Raymond M, Ulaszewska M, Troise F, Sharpe H, Morgan SB, Hinks TSC, Lambe T, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: garner lc. Science. 2021 Jan 29;371(6528):521-526. doi: 10.1126/science.aax8819. Science. 2021. PMID: 33510029 Free PMC article.
Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
Provine NM, Amini A, Garner LC, FitzPatrick MEB, Dold C, Silva Reyes L, Chinnakannan S, Oguti B, Raymond M, Troise F, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: garner lc. Eur J Immunol. 2022 May;52(5):835-837. doi: 10.1002/eji.202149367. Epub 2022 Jan 17. Eur J Immunol. 2022. PMID: 34958459 Free article.
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk; COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk, et al. Cell. 2022 Mar 3;185(5):916-938.e58. doi: 10.1016/j.cell.2022.01.012. Epub 2022 Jan 21. Cell. 2022. PMID: 35216673 Free PMC article.
31 results