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IMI European Lead Factory - democratizing access to high-throughput screening.
Jones PS, Boucharens S, McElroy SP, Morrison A, Honarnejad S, van Boeckel S, van den Hurk H, Basting D, Hüser J, Jaroch S, Ottow E, Benningshof J, Folmer RHA, Leemhuis F, Kramer-Verhulst PM, Nies VJM, Orrling KM, Rijnders T, Pfander C, Engkvist O, Pairaudeau G, Simpson PB, Ortholand JY, Roche D, Dömling A, Kühnert SM, Roevens PWM, van Vlijmen H, van Wanrooij EJA, Verbruggen C, Nussbaumer P, Ovaa H, van der Stelt M, Simonsen KB, Tagmose L, Waldmann H, Duffy J, Finsinger D, Jurzak M, Burgess-Brown NA, Lee WH, Rutjes FPJT, Haag H, Kallus C, Mors H, Dorval T, Lesur B, Ramon Olayo F, Hamza D, Jones G, Pearce C, Piechot A, Tzalis D, Clausen MH, Davis J, Derouane D, Vermeiren C, Kaiser M, Stockman RA, Barrault DV, Pannifer AD, Swedlow JR, Nelson AS, Orru RVA, Ruijter E, van Helden SP, Li VM, Vries T, de Vlieger JSB. Jones PS, et al. Among authors: vermeiren c. Nat Rev Drug Discov. 2022 Apr;21(4):245-246. doi: 10.1038/d41573-021-00196-3. Nat Rev Drug Discov. 2022. PMID: 34907316 No abstract available.
5-HT7 Receptor Antagonists with an Unprecedented Selectivity Profile.
Ates A, Burssens P, Lorthioir O, Lo Brutto P, Dehon G, Keyaerts J, Coloretti F, Lallemand B, Verbois V, Gillard M, Vermeiren C. Ates A, et al. Among authors: vermeiren c. ChemMedChem. 2018 Apr 23;13(8):795-802. doi: 10.1002/cmdc.201800026. Epub 2018 Mar 30. ChemMedChem. 2018. PMID: 29451954
Discovery of selective alpha(2C) adrenergic receptor agonists.
Jnoff E, Christophe B, Collart P, Coloretti F, Debeuckelaere A, De Ryck M, Fuks B, Genicot C, Gillard M, Guyaux M, Price N, Vandergeten MC, Vermeiren C. Jnoff E, et al. Among authors: vermeiren c. ChemMedChem. 2012 Mar 5;7(3):385-90. doi: 10.1002/cmdc.201100528. Epub 2012 Jan 19. ChemMedChem. 2012. PMID: 22262529 No abstract available.
Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation.
Merten N, Fischer J, Simon K, Zhang L, Schröder R, Peters L, Letombe AG, Hennen S, Schrage R, Bödefeld T, Vermeiren C, Gillard M, Mohr K, Lu QR, Brüstle O, Gomeza J, Kostenis E. Merten N, et al. Among authors: vermeiren c. Cell Chem Biol. 2018 Jun 21;25(6):775-786.e5. doi: 10.1016/j.chembiol.2018.03.012. Epub 2018 Apr 26. Cell Chem Biol. 2018. PMID: 29706593 Free PMC article.
Evaluating Diagnostic Accuracy of Saliva Sampling Methods for Severe Acute Respiratory Syndrome Coronavirus 2 Reveals Differential Sensitivity and Association with Viral Load.
Mestdagh P, Gillard M, Dhillon SK, Pirnay JP, Poels J, Hellemans J, Hutse V, Vermeiren C, Boutier M, De Wever V, Soentjens P, Djebara S, Malonne H, André E, Arbyn M, Smeraglia J, Vandesompele J. Mestdagh P, et al. Among authors: vermeiren c. J Mol Diagn. 2021 Oct;23(10):1249-1258. doi: 10.1016/j.jmoldx.2021.07.017. Epub 2021 Aug 3. J Mol Diagn. 2021. PMID: 34358676 Free PMC article.
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist.
Hennen S, Wang H, Peters L, Merten N, Simon K, Spinrath A, Blättermann S, Akkari R, Schrage R, Schröder R, Schulz D, Vermeiren C, Zimmermann K, Kehraus S, Drewke C, Pfeifer A, König GM, Mohr K, Gillard M, Müller CE, Lu QR, Gomeza J, Kostenis E. Hennen S, et al. Among authors: vermeiren c. Sci Signal. 2013 Oct 22;6(298):ra93. doi: 10.1126/scisignal.2004350. Sci Signal. 2013. PMID: 24150254 Free PMC article.
Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre.
Janssen R, Cuypers L, Laenen L, Keyaerts E, Beuselinck K, Janssenswillen S, Slechten B, Bode J, Wollants E, Van Laethem K, Rector A, Bloemen M, Sijmons A, de Schaetzen N, Capron A, Van Baelen K, Pascal T, Vermeiren C, Bureau F, Vandesompele J, De Smet P, Uten W, Malonne H, Kerkhofs P, De Cock J, Matheeussen V, Verhasselt B, Gillet L, Detry G, Bearzatto B, Degosserie J, Henin C, Pairoux G; COVID-19 Genomics Belgium Consortium; Maes P, Van Ranst M, Lagrou K, Dequeker E, André E. Janssen R, et al. Among authors: vermeiren c. Virol J. 2024 Feb 10;21(1):40. doi: 10.1186/s12985-024-02308-y. Virol J. 2024. PMID: 38341597 Free PMC article. Review.
38 results