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In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma.
Dayot S, Speisky D, Couvelard A, Bourgoin P, Gratio V, Cros J, Rebours V, Sauvanet A, Bedossa P, Paradis V, Ruszniewski P, Couvineau A, Voisin T. Dayot S, et al. Among authors: gratio v. Oncotarget. 2018 Jan 9;9(6):6952-6967. doi: 10.18632/oncotarget.24084. eCollection 2018 Jan 23. Oncotarget. 2018. PMID: 29467942 Free PMC article.
Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A.
Messal N, Fernandez N, Dayot S, Gratio V, Nicole P, Prochasson C, Chantret I, LeGuilloux G, Jarry A, Couvelard A, Tréton X, Voisin T, Ogier-Denis E, Couvineau A. Messal N, et al. Among authors: gratio v. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3618-3628. doi: 10.1016/j.bbadis.2018.08.023. Epub 2018 Aug 18. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251681 Free article.
The Orexin receptors: Structural and anti-tumoral properties.
Couvineau A, Nicole P, Gratio V, Voisin T. Couvineau A, et al. Among authors: gratio v. Front Endocrinol (Lausanne). 2022 Jul 28;13:931970. doi: 10.3389/fendo.2022.931970. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35966051 Free PMC article. Review.
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