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SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection.
Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, San JE, Cromer D, Scheepers C, Amoako D, Karim F, Bernstein M, Lustig G, Archary D, Smith M, Ganga Y, Jule Z, Reedoy K, Hwa SH, Giandhari J, Blackburn JM, Gosnell BI, Abdool Karim SS, Hanekom W; NGS-SA; COMMIT-KZN Team; von Gottberg A, Bhiman J, Lessells RJ, Moosa MS, Davenport MP, de Oliveira T, Moore PL, Sigal A. Cele S, et al. Among authors: karim f. medRxiv [Preprint]. 2021 Dec 17:2021.12.08.21267417. doi: 10.1101/2021.12.08.21267417. medRxiv. 2021. PMID: 34909788 Free PMC article. Updated. Preprint.
High rates of tuberculosis in patients accessing HAART in rural South Africa.
Naidoo K, Karim QA, Bhushan A, Naidoo K, Yende-Zuma N, McHunu PK, Frohlich J, Karim F, Upfold M, Kocheleff P, Abdool Karim SS. Naidoo K, et al. Among authors: karim qa, karim f. J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):438-46. doi: 10.1097/QAI.0000000000000060. J Acquir Immune Defic Syndr. 2014. PMID: 24256629 Free PMC article.
High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults.
Roider J, Maehara T, Ngoepe A, Ramsuran D, Muenchhoff M, Adland E, Aicher T, Kazer SW, Jooste P, Karim F, Kuhn W, Shalek AK, Ndung'u T, Morris L, Moore PL, Pillai S, Kløverpris H, Goulder P, Leslie A. Roider J, et al. Among authors: karim f. Front Immunol. 2018 Sep 12;9:1975. doi: 10.3389/fimmu.2018.01975. eCollection 2018. Front Immunol. 2018. PMID: 30258437 Free PMC article. Clinical Trial.
Early Detection of Emergent Extensively Drug-Resistant Tuberculosis by Flow Cytometry-Based Phenotyping and Whole-Genome Sequencing.
O'Donnell MR, Larsen MH, Brown TS, Jain P, Munsamy V, Wolf A, Uccellini L, Karim F, de Oliveira T, Mathema B, Jacobs WR, Pym A. O'Donnell MR, et al. Among authors: karim f. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e01834-18. doi: 10.1128/AAC.01834-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670422 Free PMC article.
Erratum for O'Donnell et al., "Early Detection of Emergent Extensively Drug-Resistant Tuberculosis by Flow Cytometry-Based Phenotyping and Whole-Genome Sequencing".
O'Donnell MR, Larsen MH, Brown TS, Jain P, Munsamy V, Wolf A, Uccellini L, Karim F, de Oliveira T, Mathema B, Jacobs WR, Pym A. O'Donnell MR, et al. Among authors: karim f. Antimicrob Agents Chemother. 2019 May 24;63(6):e00764-19. doi: 10.1128/AAC.00764-19. Print 2019 Jun. Antimicrob Agents Chemother. 2019. PMID: 31126923 Free PMC article. No abstract available.
Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection.
Ndlovu LN, Peetluk L, Moodley S, Nhamoyebonde S, Ngoepe AT, Mazibuko M, Khan K, Karim F, Pym AS, Maruri F, Moosa MS, van der Heijden YF, Sterling TR, Leslie A. Ndlovu LN, et al. Among authors: karim f. Front Immunol. 2020 Aug 28;11:1872. doi: 10.3389/fimmu.2020.01872. eCollection 2020. Front Immunol. 2020. PMID: 32983107 Free PMC article.
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.
Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, Gosnell BI, Hanekom W, Moosa MS; Network for Genomic Surveillance in South Africa; COMMIT-KZN Team; Lessells RJ, de Oliveira T, Sigal A. Cele S, et al. Among authors: karim f. Nature. 2021 May;593(7857):142-146. doi: 10.1038/s41586-021-03471-w. Epub 2021 Mar 29. Nature. 2021. PMID: 33780970 Free PMC article.
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave.
Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T; COVID-19 Mechanisms and Multi-omics at the Intersection of TB and HIV in KwaZulu-Natal (COMMIT-KZN Team). Snyman J, et al. Among authors: karim f. Clin Infect Dis. 2022 Aug 24;75(1):e249-e256. doi: 10.1093/cid/ciab758. Clin Infect Dis. 2022. PMID: 34472583 Free PMC article.
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.
Lustig G, Cele S, Karim F, Derache A, Ngoepe A, Khan K, Gosnell BI, Moosa MS, Ntshuba N, Marais S, Jeena PM, Govender K, Adamson J, Kløverpris H, Gupta RK, Harrichandparsad R, Patel VB, Sigal A. Lustig G, et al. Among authors: karim f. PLoS Pathog. 2021 Sep 23;17(9):e1009871. doi: 10.1371/journal.ppat.1009871. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34555123 Free PMC article.
658 results