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Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.
Zhang XJ, She ZG, Wang J, Sun D, Shen LJ, Xiang H, Cheng X, Ji YX, Huang YP, Li PL, Yang X, Cheng Y, Ma JP, Wang HP, Hu Y, Hu F, Tian S, Tian H, Zhang P, Zhao GN, Wang L, Hu ML, Yang Q, Zhu LH, Cai J, Yang J, Zhang X, Ma X, Xu Q, Touyz RM, Liu PP, Loomba R, Wang Y, Li H. Zhang XJ, et al. Among authors: zhao gn. Sci Transl Med. 2021 Dec 15;13(624):eabg8117. doi: 10.1126/scitranslmed.abg8117. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910546
A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques.
Zhang XJ, Ji YX, Cheng X, Cheng Y, Yang H, Wang J, Zhao LP, Huang YP, Sun D, Xiang H, Shen LJ, Li PL, Ma JP, Tian RF, Yang J, Yao X, Xu H, Liao R, Xiao L, Zhang P, Zhang X, Zhao GN, Wang X, Hu ML, Tian S, Wan J, Cai J, Ma X, Xu Q, Wang Y, Touyz RM, Liu PP, Loomba R, She ZG, Li H. Zhang XJ, et al. Among authors: zhao gn. Sci Transl Med. 2021 Dec 15;13(624):eabg8116. doi: 10.1126/scitranslmed.abg8116. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910548
TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease.
Zhao GN, Tian ZW, Tian T, Zhu ZP, Zhao WJ, Tian H, Cheng X, Hu FJ, Hu ML, Tian S, Ding T, Chen S, Ji YX, Zhang P, Zhang XJ, She ZG, Yuan Y, Chen W, Bai L, Li H. Zhao GN, et al. Among authors: zhao wj. Cell Metab. 2021 Aug 3;33(8):1640-1654.e8. doi: 10.1016/j.cmet.2021.05.014. Epub 2021 Jun 8. Cell Metab. 2021. PMID: 34107313 Free article.
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19.
Zhang XJ, Qin JJ, Cheng X, Shen L, Zhao YC, Yuan Y, Lei F, Chen MM, Yang H, Bai L, Song X, Lin L, Xia M, Zhou F, Zhou J, She ZG, Zhu L, Ma X, Xu Q, Ye P, Chen G, Liu L, Mao W, Yan Y, Xiao B, Lu Z, Peng G, Liu M, Yang J, Yang L, Zhang C, Lu H, Xia X, Wang D, Liao X, Wei X, Zhang BH, Zhang X, Yang J, Zhao GN, Zhang P, Liu PP, Loomba R, Ji YX, Xia J, Wang Y, Cai J, Guo J, Li H. Zhang XJ, et al. Among authors: zhao gn, zhao yc. Cell Metab. 2020 Aug 4;32(2):176-187.e4. doi: 10.1016/j.cmet.2020.06.015. Epub 2020 Jun 24. Cell Metab. 2020. PMID: 32592657 Free PMC article.
The Neutrophil-to-Lymphocyte Ratio Determines Clinical Efficacy of Corticosteroid Therapy in Patients with COVID-19.
Cai J, Li H, Zhang C, Chen Z, Liu H, Lei F, Qin JJ, Liu YM, Zhou F, Song X, Zhou J, Zhao YC, Wu B, He M, Yang H, Zhu L, Zhang P, Ji YX, Zhao GN, Lu Z, Liu L, Mao W, Liao X, Lu H, Wang D, Xia X, Huang X, Wei X, Xia J, Zhang BH, Yuan Y, She ZG, Xu Q, Ma X, Wang Y, Yang J, Zhang X, Zhang XJ, Li H. Cai J, et al. Among authors: zhao gn, zhao yc. Cell Metab. 2021 Feb 2;33(2):258-269.e3. doi: 10.1016/j.cmet.2021.01.002. Epub 2021 Jan 5. Cell Metab. 2021. PMID: 33421384 Free PMC article.
Wang et al. reply.
Wang PX, Zhao GN, Ji YX, Zhang P, Zhang XJ, Gong J, Zhao LP, Yan ZZ, Yin M, Jiang Z, Shen LJ, Yang X, Fang J, Tian S, Tong J, Wang Y, Zhu XY, Zhang X, Wei QF, Wang Y, Xie Q, Li J, Wan L, She ZG, Wang Z, Huang Z, Li H. Wang PX, et al. Among authors: zhao gn, zhao lp. Nat Med. 2018 Jun;24(6):700-701. doi: 10.1038/s41591-018-0063-1. Nat Med. 2018. PMID: 29867231 No abstract available.
34 results