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VLDLR and ApoER2 are receptors for multiple alphaviruses.
Clark LE, Clark SA, Lin C, Liu J, Coscia A, Nabel KG, Yang P, Neel DV, Lee H, Brusic V, Stryapunina I, Plante KS, Ahmed AA, Catteruccia F, Young-Pearse TL, Chiu IM, Llopis PM, Weaver SC, Abraham J. Clark LE, et al. Nature. 2022 Feb;602(7897):475-480. doi: 10.1038/s41586-021-04326-0. Epub 2021 Dec 20. Nature. 2022. PMID: 34929721 Free PMC article.
INPP5D regulates inflammasome activation in human microglia.
Chou V, Pearse RV 2nd, Aylward AJ, Ashour N, Taga M, Terzioglu G, Fujita M, Fancher SB, Sigalov A, Benoit CR, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL. Chou V, et al. Among authors: young pearse tl. Nat Commun. 2023 Nov 29;14(1):7552. doi: 10.1038/s41467-023-42819-w. Nat Commun. 2023. PMID: 38016942 Free PMC article.
Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.
Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV 2nd, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL. Fujita M, et al. Nat Genet. 2024 Apr;56(4):605-614. doi: 10.1038/s41588-024-01685-y. Epub 2024 Mar 21. Nat Genet. 2024. PMID: 38514782
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL. Klein HU, et al. Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559478 Free PMC article.
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. Mostafavi S, et al. Nat Neurosci. 2018 Jun;21(6):811-819. doi: 10.1038/s41593-018-0154-9. Epub 2018 May 25. Nat Neurosci. 2018. PMID: 29802388 Free PMC article.
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV 2nd, Lish AM, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Taga MF, Huynh K, Arnold M, Meikle PJ, De Jager PL, Menon V, Young JE, Young-Pearse TL. Lee H, et al. Among authors: young pearse tl. Cell Rep. 2023 Aug 29;42(8):112994. doi: 10.1016/j.celrep.2023.112994. Epub 2023 Aug 22. Cell Rep. 2023. PMID: 37611586 Free PMC article.
69 results