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A Pan-Respiratory Antiviral Chemotype Targeting a Host Multi-Protein Complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad MD, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: muller schiffmann a. bioRxiv [Preprint]. 2023 Dec 12:2021.01.17.426875. doi: 10.1101/2021.01.17.426875. bioRxiv. 2023. PMID: 34931190 Free PMC article. Preprint.
All-d-Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors.
Bocharov EV, Gremer L, Urban AS, Okhrimenko IS, Volynsky PE, Nadezhdin KD, Bocharova OV, Kornilov DA, Zagryadskaya YA, Kamynina AV, Kuzmichev PK, Kutzsche J, Bolakhrif N, Müller-Schiffmann A, Dencher NA, Arseniev AS, Efremov RG, Gordeliy VI, Willbold D. Bocharov EV, et al. Among authors: muller schiffmann a. J Med Chem. 2021 Nov 25;64(22):16464-16479. doi: 10.1021/acs.jmedchem.1c00632. Epub 2021 Nov 5. J Med Chem. 2021. PMID: 34739758
SARS-CoV-2 targets neurons of 3D human brain organoids.
Ramani A, Müller L, Ostermann PN, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J. Ramani A, et al. Among authors: muller schiffmann a. EMBO J. 2020 Oct 15;39(20):e106230. doi: 10.15252/embj.2020106230. Epub 2020 Sep 23. EMBO J. 2020. PMID: 32876341 Free PMC article.
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation.
Marreiros R, Müller-Schiffmann A, Trossbach SV, Prikulis I, Hänsch S, Weidtkamp-Peters S, Moreira AR, Sahu S, Soloviev I, Selvarajah S, Lingappa VR, Korth C. Marreiros R, et al. Among authors: muller schiffmann a. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6741-6751. doi: 10.1073/pnas.1906466117. Epub 2020 Mar 9. Proc Natl Acad Sci U S A. 2020. PMID: 32152117 Free PMC article.
Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
Yerabham ASK, Müller-Schiffmann A, Ziehm T, Stadler A, Köber S, Indurkhya X, Marreiros R, Trossbach SV, Bradshaw NJ, Prikulis I, Willbold D, Weiergräber OH, Korth C. Yerabham ASK, et al. Among authors: muller schiffmann a. PLoS One. 2018 Jan 11;13(1):e0191162. doi: 10.1371/journal.pone.0191162. eCollection 2018. PLoS One. 2018. PMID: 29324815 Free PMC article.
34 results