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Human MAIT cells respond to and suppress HIV-1.
Phetsouphanh C, Phalora P, Hackstein CP, Thornhill J, Munier CML, Meyerowitz J, Murray L, VanVuuren C, Goedhals D, Drexhage L, Moore R, Sattentau QJ, Mak JY, Fairlie DP, Fidler S, Kelleher AD, Frater J, Klenerman P. Phetsouphanh C, et al. Among authors: goedhals d. Elife. 2021 Dec 24;10:e50324. doi: 10.7554/eLife.50324. Elife. 2021. PMID: 34951583 Free PMC article.
HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.
Matthews PC, Adland E, Listgarten J, Leslie A, Mkhwanazi N, Carlson JM, Harndahl M, Stryhn A, Payne RP, Ogwu A, Huang KH, Frater J, Paioni P, Kloverpris H, Jooste P, Goedhals D, van Vuuren C, Steyn D, Riddell L, Chen F, Luzzi G, Balachandran T, Ndung'u T, Buus S, Carrington M, Shapiro R, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: goedhals d. J Immunol. 2011 May 15;186(10):5675-86. doi: 10.4049/jimmunol.1003711. Epub 2011 Apr 15. J Immunol. 2011. PMID: 21498667 Free PMC article.
Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations.
Huang KH, Goedhals D, Carlson JM, Brockman MA, Mishra S, Brumme ZL, Hickling S, Tang CS, Miura T, Seebregts C, Heckerman D, Ndung'u T, Walker B, Klenerman P, Steyn D, Goulder P, Phillips R; Bloemfontein-Oxford Collaborative Group; van Vuuren C, Frater J. Huang KH, et al. Among authors: goedhals d. PLoS One. 2011 Apr 22;6(4):e19018. doi: 10.1371/journal.pone.0019018. PLoS One. 2011. PMID: 21544209 Free PMC article.
HIV control through a single nucleotide on the HLA-B locus.
Kløverpris HN, Harndahl M, Leslie AJ, Carlson JM, Ismail N, van der Stok M, Huang KH, Chen F, Riddell L, Steyn D, Goedhals D, van Vuuren C, Frater J, Walker BD, Carrington M, Ndung'u T, Buus S, Goulder P. Kløverpris HN, et al. Among authors: goedhals d. J Virol. 2012 Nov;86(21):11493-500. doi: 10.1128/JVI.01020-12. Epub 2012 Aug 15. J Virol. 2012. PMID: 22896606 Free PMC article.
Co-operative additive effects between HLA alleles in control of HIV-1.
Matthews PC, Listgarten J, Carlson JM, Payne R, Huang KH, Frater J, Goedhals D, Steyn D, van Vuuren C, Paioni P, Jooste P, Ogwu A, Shapiro R, Mncube Z, Ndung'u T, Walker BD, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: goedhals d. PLoS One. 2012;7(10):e47799. doi: 10.1371/journal.pone.0047799. Epub 2012 Oct 19. PLoS One. 2012. PMID: 23094091 Free PMC article.
Prevalence of Antiretroviral Drug Resistance in Patients Who Are Not Responding to Protease Inhibitor-Based Treatment: Results From the First National Survey in South Africa.
Steegen K, Bronze M, Papathanasopoulos MA, van Zyl G, Goedhals D, Van Vuuren C, Macleod W, Sanne I, Stevens WS, Carmona SC. Steegen K, et al. Among authors: goedhals d. J Infect Dis. 2016 Dec 15;214(12):1826-1830. doi: 10.1093/infdis/jiw491. Epub 2016 Oct 20. J Infect Dis. 2016. PMID: 27923946
Mapping the drivers of within-host pathogen evolution using massive data sets.
Palmer DS, Turner I, Fidler S, Frater J, Goedhals D, Goulder P, Huang KG, Oxenius A, Phillips R, Shapiro R, Vuuren CV, McLean AR, McVean G. Palmer DS, et al. Among authors: goedhals d. Nat Commun. 2019 Jul 9;10(1):3017. doi: 10.1038/s41467-019-10724-w. Nat Commun. 2019. PMID: 31289267 Free PMC article.
Maintenance of Functional CD57+ Cytolytic CD4+ T Cells in HIV+ Elite Controllers.
Phetsouphanh C, Aldridge D, Marchi E, Munier CML, Meyerowitz J, Murray L, Van Vuuren C, Goedhals D, Fidler S, Kelleher A, Klenerman P, Frater J. Phetsouphanh C, et al. Among authors: goedhals d. Front Immunol. 2019 Aug 8;10:1844. doi: 10.3389/fimmu.2019.01844. eCollection 2019. Front Immunol. 2019. PMID: 31440240 Free PMC article.
56 results