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Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice.
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, LeeMontiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, Dickmander R, Baric R, Pearce KH, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. Among authors: ekins s. bioRxiv [Preprint]. 2021 Dec 20:2021.12.16.472155. doi: 10.1101/2021.12.16.472155. bioRxiv. 2021. PMID: 34981062 Free PMC article. Preprint.
Computational drug repositioning identifies niclosamide and tribromsalan as inhibitors of Mycobacterium tuberculosis and Mycobacterium abscessus.
Yang JJ, Goff A, Wild DJ, Ding Y, Annis A, Kerber R, Foote B, Passi A, Duerksen JL, London S, Puhl AC, Lane TR, Braunstein M, Waddell SJ, Ekins S. Yang JJ, et al. Among authors: ekins s. Tuberculosis (Edinb). 2024 May;146:102500. doi: 10.1016/j.tube.2024.102500. Epub 2024 Feb 27. Tuberculosis (Edinb). 2024. PMID: 38432118 Free article.
Synthesis and Evaluation of 9-Aminoacridines with SARS-CoV-2 Antiviral Activity.
Jones T, Monakhova N, Guivel-Benhassine F, Lepioshkin A, Bruel T, Lane TR, Schwartz O, Puhl AC, Makarov V, Ekins S. Jones T, et al. Among authors: ekins s. ACS Omega. 2023 Oct 19;8(43):40817-40822. doi: 10.1021/acsomega.3c05900. eCollection 2023 Oct 31. ACS Omega. 2023. PMID: 37929131 Free PMC article.
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents.
Linciano P, Quotadamo A, Luciani R, Santucci M, Zorn KM, Foil DH, Lane TR, Cordeiro da Silva A, Santarem N, B Moraes C, Freitas-Junior L, Wittig U, Mueller W, Tonelli M, Ferrari S, Venturelli A, Gul S, Kuzikov M, Ellinger B, Reinshagen J, Ekins S, Costi MP. Linciano P, et al. Among authors: ekins s. J Med Chem. 2023 Nov 23;66(22):15230-15255. doi: 10.1021/acs.jmedchem.3c01322. Epub 2023 Nov 3. J Med Chem. 2023. PMID: 37921561 Free PMC article.
371 results