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Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice.
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, LeeMontiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, Dickmander R, Baric R, Pearce KH, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. bioRxiv [Preprint]. 2021 Dec 20:2021.12.16.472155. doi: 10.1101/2021.12.16.472155. bioRxiv. 2021. PMID: 34981062 Free PMC article. Preprint.
Crystallographic structure and molecular dynamics simulations of the major endoglucanase from Xanthomonas campestris pv. campestris shed light on its oligosaccharide products release pattern.
Puhl AC, Prates ET, Rosseto FR, Manzine LR, Stankovic I, de Araújo SS, Alvarez TM, Squina FM, Skaf MS, Polikarpov I. Puhl AC, et al. Int J Biol Macromol. 2019 Sep 1;136:493-502. doi: 10.1016/j.ijbiomac.2019.06.107. Epub 2019 Jun 16. Int J Biol Macromol. 2019. PMID: 31216447
Structural dataset for the PPARγ V290M mutant.
Puhl AC, Webb P, Polikarpov I. Puhl AC, et al. Data Brief. 2016 Apr 4;7:1430-1437. doi: 10.1016/j.dib.2016.03.082. eCollection 2016 Jun. Data Brief. 2016. PMID: 27761505 Free PMC article.
Crystallization and preliminary diffraction analysis of the catalytic domain of major extracellular endoglucanase from Xanthomonas campestris pv. campestris.
Rosseto FR, Puhl AC, Andrade MO, Polikarpov I. Rosseto FR, et al. Among authors: puhl ac. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Feb 1;69(Pt 2):137-40. doi: 10.1107/S1744309112051408. Epub 2013 Jan 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23385754 Free PMC article.
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Ramanjulu JM, Pesiridis GS, Yang J, Concha N, Singhaus R, Zhang SY, Tran JL, Moore P, Lehmann S, Eberl HC, Muelbaier M, Schneck JL, Clemens J, Adam M, Mehlmann J, Romano J, Morales A, Kang J, Leister L, Graybill TL, Charnley AK, Ye G, Nevins N, Behnia K, Wolf AI, Kasparcova V, Nurse K, Wang L, Puhl AC, Li Y, Klein M, Hopson CB, Guss J, Bantscheff M, Bergamini G, Reilly MA, Lian Y, Duffy KJ, Adams J, Foley KP, Gough PJ, Marquis RW, Smothers J, Hoos A, Bertin J. Ramanjulu JM, et al. Among authors: puhl ac. Nature. 2018 Dec;564(7736):439-443. doi: 10.1038/s41586-018-0705-y. Epub 2018 Nov 7. Nature. 2018. PMID: 30405246
Mode of peroxisome proliferator-activated receptor γ activation by luteolin.
Puhl AC, Bernardes A, Silveira RL, Yuan J, Campos JL, Saidemberg DM, Palma MS, Cvoro A, Ayers SD, Webb P, Reinach PS, Skaf MS, Polikarpov I. Puhl AC, et al. Mol Pharmacol. 2012 Jun;81(6):788-99. doi: 10.1124/mol.111.076216. Epub 2012 Mar 5. Mol Pharmacol. 2012. PMID: 22391103
New targets for HIV drug discovery.
Puhl AC, Garzino Demo A, Makarov VA, Ekins S. Puhl AC, et al. Drug Discov Today. 2019 May;24(5):1139-1147. doi: 10.1016/j.drudis.2019.03.013. Epub 2019 Mar 15. Drug Discov Today. 2019. PMID: 30885676 Free PMC article. Review.
48 results