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Page 1
Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.
McManus DT, Valanparambil RM, Medina CB, Hu Y, Scharer CD, Sobierajska E, Chang DY, Wieland A, Lee J, Nasti TH, Hashimoto M, Ross JL, Prokhnevska N, Cardenas MA, Gill AL, Clark EC, Abadie K, Kueh HY, Kaye J, Au-Yeung BB, Kissick HT, Ahmed R. McManus DT, et al. Among authors: valanparambil rm. Res Sq [Preprint]. 2024 Feb 12:rs.3.rs-3922168. doi: 10.21203/rs.3.rs-3922168/v1. Res Sq. 2024. PMID: 38410458 Free PMC article. Preprint.
Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision.
Abadie K, Clark EC, Valanparambil RM, Ukogu O, Yang W, Daza RM, Ng KKH, Fathima J, Wang AL, Lee J, Nasti TH, Bhandoola A, Nourmohammad A, Ahmed R, Shendure J, Cao J, Kueh HY. Abadie K, et al. Among authors: valanparambil rm. Immunity. 2024 Feb 13;57(2):271-286.e13. doi: 10.1016/j.immuni.2023.12.006. Epub 2024 Jan 31. Immunity. 2024. PMID: 38301652 Free article.
BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer.
Valanparambil RM, Lai L, Johns MA, Davis-Gardner M, Linderman SL, McPherson TO, Chang A, Akhtar A, Gamarra ELB, Matia H, McCook-Veal AA, Switchenko J, Nasti TH, Green F, Saini M, Wieland A, Pinsky BA, Solis D, Dhodapkar MV, Carlisle J, Ramalingam S, Ahmed R, Suthar MS. Valanparambil RM, et al. NPJ Vaccines. 2023 Nov 21;8(1):179. doi: 10.1038/s41541-023-00779-8. NPJ Vaccines. 2023. PMID: 37990024 Free PMC article.
Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.
Rodilla AM, Valanparambil RM, Mack PC, Hsu CY, Cagan J, Tavolacci SC, Carreño JM, Brody R, Moore A, King JC, Gomez JE, Rohs N, Rolfo C, Bunn PA Jr, Gerber DE, Minna JD, Krammer F, Ramalingam SS, García-Sastre A, Shyr Y, Ahmed R, Hirsch FR. Rodilla AM, et al. Among authors: valanparambil rm. Cancer Cell. 2023 Nov 13;41(11):1838-1840. doi: 10.1016/j.ccell.2023.09.017. Epub 2023 Oct 19. Cancer Cell. 2023. PMID: 37863065
Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron.
Patel A, Kumar S, Lai L, Keen M, Valanparambil R, Chakravarthy C, Laughlin Z, Frank F, Cheedarla N, Verkerke HP, Neish AS, Roback JD, Davis CW, Wrammert J, Sharma A, Ahmed R, Suthar MS, Murali-Krishna K, Chandele A, Ortlund E. Patel A, et al. Among authors: valanparambil r. Cell Rep. 2023 Sep 26;42(9):113150. doi: 10.1016/j.celrep.2023.113150. Epub 2023 Sep 13. Cell Rep. 2023. PMID: 37708028 Free PMC article.
Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, Cheedarla N, Verkerke HP, Frank F, Neish AS, Roback JD, Davis CW, Wrammert J, Ahmed R, Suthar MS, Sharma A, Murali-Krishna K, Chandele A, Ortlund EA. Patel A, et al. Among authors: valanparambil r. Structure. 2023 Jul 6;31(7):801-811.e5. doi: 10.1016/j.str.2023.04.010. Epub 2023 May 11. Structure. 2023. PMID: 37167972 Free PMC article.
Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies.
Chang A, Akhtar A, Lai L, Orellana-Noia VM, Linderman SL, McCook-Veal AA, Switchenko JM, Saini M, Valanparambil RM, Blum KA, Allen PB, Lechowicz MJ, Romancik JT, Ayers A, Leal A, O'Leary CB, Churnetski MC, Baird K, Kives M, Wrammert J, Nooka AK, Koff JL, Dhodapkar MV, Suthar MS, Cohen JB, Ahmed R. Chang A, et al. Among authors: valanparambil rm. Cancer Res Commun. 2022 Dec;2(12):1684-1692. doi: 10.1158/2767-9764.crc-22-0471. Cancer Res Commun. 2022. PMID: 36644323 Free PMC article.
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
Prokhnevska N, Cardenas MA, Valanparambil RM, Sobierajska E, Barwick BG, Jansen C, Reyes Moon A, Gregorova P, delBalzo L, Greenwald R, Bilen MA, Alemozaffar M, Joshi S, Cimmino C, Larsen C, Master V, Sanda M, Kissick H. Prokhnevska N, et al. Among authors: valanparambil rm. Immunity. 2023 Jan 10;56(1):107-124.e5. doi: 10.1016/j.immuni.2022.12.002. Epub 2022 Dec 28. Immunity. 2023. PMID: 36580918 Free PMC article.
Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.
Azeem MI, Nooka AK, Shanmugasundaram U, Cheedarla N, Potdar S, Manalo RJ, Moreno A, Switchenko JM, Cheedarla S, Doxie DB, Radzievski R, Ellis ML, Manning KE, Wali B, Valanparambil RM, Maples KT, Baymon E, Kaufman JL, Hofmeister CC, Joseph NS, Lonial S, Roback JD, Sette A, Ahmed R, Suthar MS, Neish AS, Dhodapkar MV, Dhodapkar KM. Azeem MI, et al. Among authors: valanparambil rm. Blood Cancer Discov. 2023 Mar 1;4(2):106-117. doi: 10.1158/2643-3230.BCD-22-0173. Blood Cancer Discov. 2023. PMID: 36511813 Free PMC article.
26 results