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Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity.
Xiong Y, Liu T, Chen T, Hansen J, Hu B, Chen Y, Jayaraman G, Schürer S, Vidovic D, Goldfarb J, Sobie EA, Birtwistle MR, Iyengar R, Li H, Azeloglu EU. Xiong Y, et al. Among authors: jayaraman g. Sci Data. 2022 Jan 20;9(1):18. doi: 10.1038/s41597-021-01114-3. Sci Data. 2022. PMID: 35058449 Free PMC article.
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity.
van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, Azeloglu EU, Iyengar R. van Hasselt JGC, et al. Among authors: jayaraman g. Nat Commun. 2020 Sep 23;11(1):4809. doi: 10.1038/s41467-020-18396-7. Nat Commun. 2020. PMID: 32968055 Free PMC article.
A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.
Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR. Xiong Y, et al. Among authors: jayaraman g. Sci Rep. 2017 Nov 7;7(1):14626. doi: 10.1038/s41598-017-14892-x. Sci Rep. 2017. PMID: 29116112 Free PMC article.
Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.
Calizo RC, Bhattacharya S, van Hasselt JGC, Wei C, Wong JS, Wiener RJ, Ge X, Wong NJ, Lee JJ, Cuttitta CM, Jayaraman G, Au VH, Janssen W, Liu T, Li H, Salem F, Jaimes EA, Murphy B, Campbell KN, Azeloglu EU. Calizo RC, et al. Among authors: jayaraman g. Nat Commun. 2019 May 3;10(1):2061. doi: 10.1038/s41467-019-09936-x. Nat Commun. 2019. PMID: 31053734 Free PMC article.
A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals.
Schaniel C, Dhanan P, Hu B, Xiong Y, Raghunandan T, Gonzalez DM, Dariolli R, D'Souza SL, Yadaw AS, Hansen J, Jayaraman G, Mathew B, Machado M, Berger SI, Tripodi J, Najfeld V, Garg J, Miller M, Surlyn CS, Michelis KC, Tangirala NC, Weerahandi H, Thomas DC, Beaumont KG, Sebra R, Mahajan M, Schadt E, Vidovic D, Schürer SC, Goldfarb J, Azeloglu EU, Birtwistle MR, Sobie EA, Kovacic JC, Dubois NC, Iyengar R. Schaniel C, et al. Among authors: jayaraman g. Stem Cell Reports. 2021 Dec 14;16(12):3036-3049. doi: 10.1016/j.stemcr.2021.10.005. Epub 2021 Nov 4. Stem Cell Reports. 2021. PMID: 34739849 Free PMC article.
Interconnected network motifs control podocyte morphology and kidney function.
Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R. Azeloglu EU, et al. Among authors: jayaraman g. Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621. Sci Signal. 2014. PMID: 24497609 Free PMC article.
Cell shape information is transduced through tension-independent mechanisms.
Ron A, Azeloglu EU, Calizo RC, Hu M, Bhattacharya S, Chen Y, Jayaraman G, Lee S, Neves-Zaph SR, Li H, Gordon RE, He JC, Hone JC, Iyengar R. Ron A, et al. Among authors: jayaraman g. Nat Commun. 2017 Dec 15;8(1):2145. doi: 10.1038/s41467-017-02218-4. Nat Commun. 2017. PMID: 29247198 Free PMC article.
234 results