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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model.
Kumar S, Schoonderwoerd MJA, Kroonen JS, de Graaf IJ, Sluijter M, Ruano D, González-Prieto R, Verlaan-de Vries M, Rip J, Arens R, de Miranda NFCC, Hawinkels LJAC, van Hall T, Vertegaal ACO. Kumar S, et al. Among authors: verlaan de vries m. Gut. 2022 Nov;71(11):2266-2283. doi: 10.1136/gutjnl-2021-324834. Epub 2022 Jan 24. Gut. 2022. PMID: 35074907 Free PMC article.
Uncovering global SUMOylation signaling networks in a site-specific manner.
Hendriks IA, D'Souza RC, Yang B, Verlaan-de Vries M, Mann M, Vertegaal AC. Hendriks IA, et al. Among authors: verlaan de vries m. Nat Struct Mol Biol. 2014 Oct;21(10):927-36. doi: 10.1038/nsmb.2890. Epub 2014 Sep 14. Nat Struct Mol Biol. 2014. PMID: 25218447 Free PMC article.
Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation.
Liebelt F, Schimmel J, Verlaan-de Vries M, Klemann E, van Royen ME, van der Weegen Y, Luijsterburg MS, Mullenders LH, Pines A, Vermeulen W, Vertegaal ACO. Liebelt F, et al. Among authors: verlaan de vries m. Nucleic Acids Res. 2020 Jan 10;48(1):231-248. doi: 10.1093/nar/gkz977. Nucleic Acids Res. 2020. PMID: 31722399 Free PMC article.
SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.
Hendriks IA, Treffers LW, Verlaan-de Vries M, Olsen JV, Vertegaal ACO. Hendriks IA, et al. Among authors: verlaan de vries m. Cell Rep. 2015 Mar 17;10(10):1778-1791. doi: 10.1016/j.celrep.2015.02.033. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772364 Free PMC article.
Chk2 mediates RITA-induced apoptosis.
de Lange J, Verlaan-de Vries M, Teunisse AF, Jochemsen AG. de Lange J, et al. Cell Death Differ. 2012 Jun;19(6):980-9. doi: 10.1038/cdd.2011.182. Epub 2011 Dec 9. Cell Death Differ. 2012. PMID: 22158418 Free PMC article.
24 results