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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model.
Kumar S, Schoonderwoerd MJA, Kroonen JS, de Graaf IJ, Sluijter M, Ruano D, González-Prieto R, Verlaan-de Vries M, Rip J, Arens R, de Miranda NFCC, Hawinkels LJAC, van Hall T, Vertegaal ACO. Kumar S, et al. Among authors: vertegaal aco. Gut. 2022 Nov;71(11):2266-2283. doi: 10.1136/gutjnl-2021-324834. Epub 2022 Jan 24. Gut. 2022. PMID: 35074907 Free PMC article.
SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.
Hendriks IA, Treffers LW, Verlaan-de Vries M, Olsen JV, Vertegaal ACO. Hendriks IA, et al. Among authors: vertegaal aco. Cell Rep. 2015 Mar 17;10(10):1778-1791. doi: 10.1016/j.celrep.2015.02.033. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772364 Free PMC article.
SUMO targets the APC/C to regulate transition from metaphase to anaphase.
Eifler K, Cuijpers SAG, Willemstein E, Raaijmakers JA, El Atmioui D, Ovaa H, Medema RH, Vertegaal ACO. Eifler K, et al. Among authors: vertegaal aco. Nat Commun. 2018 Mar 16;9(1):1119. doi: 10.1038/s41467-018-03486-4. Nat Commun. 2018. PMID: 29549242 Free PMC article.
97 results