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Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion.
Cell Rep. 2022 Jan 25;38(4):110227. doi: 10.1016/j.celrep.2021.110227.
Cell Rep. 2022.
PMID: 35081338
Free PMC article.
Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus.
Moore KM, Desai A, Delgado BL, Trabulo SMD, Reader C, Brown NF, Murray ER, Brentnall A, Howard P, Masterson L, Zammarchi F, Hartley JA, van Berkel PH, Marshall JF.
Moore KM, et al.
Theranostics. 2020 Feb 12;10(7):2930-2942. doi: 10.7150/thno.38702. eCollection 2020.
Theranostics. 2020.
PMID: 32194845
Free PMC article.
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The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.
Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB, Chang D, Bailey P, Scarpa A, Lawlor R, Chelala C, Keyse SM, Biankin A, Morton JP, Evans TJ, Barry ST, Sansom OJ, Kocher HM, Marshall JF.
Reader CS, et al.
J Pathol. 2019 Nov;249(3):332-342. doi: 10.1002/path.5320. Epub 2019 Jul 30.
J Pathol. 2019.
PMID: 31259422
Free PMC article.
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A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance.
Yap TA, LoRusso PM, Wong DJ, Hu-Lieskovan S, Papadopoulos KP, Holz JB, Grabowska U, Gradinaru C, Leung KM, Marshall S, Reader CS, Russell R, Sainson RCA, Seal CJ, Shepherd CJ, Germaschewski F, Gliddon D, Stern O, Young L, Brewis N, Kayitalire L, Morrow M.
Yap TA, et al. Among authors: reader cs.
Clin Cancer Res. 2023 Mar 1;29(5):888-898. doi: 10.1158/1078-0432.CCR-22-1449.
Clin Cancer Res. 2023.
PMID: 36342102
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