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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment.
Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, Eskiocak O, Parks OB, Berisha A, McAleer JP, Good M, Hoshino M, Blumberg R, Bialkowska AB, Gaffen SL, Kolls JK, Yang VW, Beyaz S, Cadwell K, Kumar P. Lin X, et al. Among authors: gaffen sl. Immunity. 2022 Feb 8;55(2):237-253.e8. doi: 10.1016/j.immuni.2021.12.016. Epub 2022 Jan 25. Immunity. 2022. PMID: 35081371 Free PMC article.
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis.
Lin Y, Ritchea S, Logar A, Slight S, Messmer M, Rangel-Moreno J, Guglani L, Alcorn JF, Strawbridge H, Park SM, Onishi R, Nyugen N, Walter MJ, Pociask D, Randall TD, Gaffen SL, Iwakura Y, Kolls JK, Khader SA. Lin Y, et al. Among authors: gaffen sl. Immunity. 2009 Nov 20;31(5):799-810. doi: 10.1016/j.immuni.2009.08.025. Epub 2009 Oct 22. Immunity. 2009. PMID: 19853481 Free PMC article.
MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.
Garg AV, Amatya N, Chen K, Cruz JA, Grover P, Whibley N, Conti HR, Hernandez Mir G, Sirakova T, Childs EC, Smithgall TE, Biswas PS, Kolls JK, McGeachy MJ, Kolattukudy PE, Gaffen SL. Garg AV, et al. Among authors: gaffen sl. Immunity. 2015 Sep 15;43(3):475-87. doi: 10.1016/j.immuni.2015.07.021. Epub 2015 Aug 25. Immunity. 2015. PMID: 26320658 Free PMC article.
Gut-Busters: IL-17 Ain't Afraid of No IL-23.
Whibley N, Gaffen SL. Whibley N, et al. Among authors: gaffen sl. Immunity. 2015 Oct 20;43(4):620-2. doi: 10.1016/j.immuni.2015.10.001. Immunity. 2015. PMID: 26488809 Free PMC article.
IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.
Chen K, Eddens T, Trevejo-Nunez G, Way EE, Elsegeiny W, Ricks DM, Garg AV, Erb CJ, Bo M, Wang T, Chen W, Lee JS, Gaffen SL, Kolls JK. Chen K, et al. Among authors: gaffen sl. Cell Host Microbe. 2016 Nov 9;20(5):596-605. doi: 10.1016/j.chom.2016.10.003. Epub 2016 Oct 27. Cell Host Microbe. 2016. PMID: 27923703 Free PMC article.
IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.
Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL. Conti HR, et al. Among authors: gaffen sl. Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27. Cell Host Microbe. 2016. PMID: 27923704 Free PMC article.
149 results