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Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil PR, Stern M, Priller A, Willmann A, Almanzar G, Vogel E, Feuerherd M, Cheng CC, Yazici S, Christa C, Jeske S, Lupoli G, Vogt T, Albanese M, Mejías-Pérez E, Bauernfried S, Graf N, Mijocevic H, Vu M, Tinnefeld K, Wettengel J, Hoffmann D, Muenchhoff M, Daechert C, Mairhofer H, Krebs S, Fingerle V, Graf A, Steininger P, Blum H, Hornung V, Liebl B, Überla K, Prelog M, Knolle P, Keppler OT, Protzer U. Wratil PR, et al. Among authors: feuerherd m. Nat Med. 2022 Mar;28(3):496-503. doi: 10.1038/s41591-022-01715-4. Epub 2022 Jan 28. Nat Med. 2022. PMID: 35090165
Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA).
Klüpfel J, Koros RC, Dehne K, Ungerer M, Würstle S, Mautner J, Feuerherd M, Protzer U, Hayden O, Elsner M, Seidel M. Klüpfel J, et al. Among authors: feuerherd m. Anal Bioanal Chem. 2021 Sep;413(22):5619-5632. doi: 10.1007/s00216-021-03315-6. Epub 2021 May 13. Anal Bioanal Chem. 2021. PMID: 33983466 Free PMC article.
Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein.
Svilenov HL, Sacherl J, Reiter A, Wolff LS, Cheng CC, Stern M, Grass V, Feuerherd M, Wachs FP, Simonavicius N, Pippig S, Wolschin F, Keppler OT, Buchner J, Brockmeyer C, Protzer U. Svilenov HL, et al. Among authors: feuerherd m. Antiviral Res. 2021 Dec;196:105197. doi: 10.1016/j.antiviral.2021.105197. Epub 2021 Nov 10. Antiviral Res. 2021. PMID: 34774603 Free PMC article.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike S, Cheng CC, Feuerherd M, Velkov S, Baldassi D, Afridi SQ, Porras-Gonzalez D, Wei X, Hagen P, Kneidinger N, Stoleriu MG, Grass V, Burgstaller G, Pichlmair A, Merkel OM, Ko C, Michler T. Ambike S, et al. Among authors: feuerherd m. Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248. Nucleic Acids Res. 2022. PMID: 34928377 Free PMC article.
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents.
Koerber N, Priller A, Yazici S, Bauer T, Cheng CC, Mijočević H, Wintersteller H, Jeske S, Vogel E, Feuerherd M, Tinnefeld K, Winter C, Ruland J, Gerhard M, Haller B, Christa C, Zelger O, Roggendorf H, Halle M, Erber J, Lingor P, Keppler O, Zehn D, Protzer U, Knolle PA. Koerber N, et al. Among authors: feuerherd m. Nat Commun. 2022 Jan 10;13(1):153. doi: 10.1038/s41467-021-27649-y. Nat Commun. 2022. PMID: 35013191 Free PMC article.
Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonism.
Jakwerth CA, Feuerherd M, Guerth FM, Oelsner M, Schellhammer L, Giglberger J, Pechtold L, Jerin C, Kugler L, Mogler C, Haller B, Erb A, Wollenberg B, Spinner CD, Buch T, Protzer U, Schmidt-Weber CB, Zissler UM, Chaker AM. Jakwerth CA, et al. Among authors: feuerherd m. J Mol Med (Berl). 2022 Apr;100(4):613-627. doi: 10.1007/s00109-022-02182-7. Epub 2022 Mar 5. J Mol Med (Berl). 2022. PMID: 35247068 Free PMC article.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
Baldassi D, Ambike S, Feuerherd M, Cheng CC, Peeler DJ, Feldmann DP, Porras-Gonzalez DL, Wei X, Keller LA, Kneidinger N, Stoleriu MG, Popp A, Burgstaller G, Pun SH, Michler T, Merkel OM. Baldassi D, et al. Among authors: feuerherd m. J Control Release. 2022 May;345:661-674. doi: 10.1016/j.jconrel.2022.03.051. Epub 2022 Mar 29. J Control Release. 2022. PMID: 35364120 Free PMC article.
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.
Nückel J, Planatscher E, Mohr AW, Deichl K, Mijočević H, Feuerherd M, Wolff L, Erber J, Schneider J, Quante M, Winter C, Ruland J, Hapfelmeier A, Hammerschmidt W, Moosmann A, Protzer U, Behrends U, Mautner J. Nückel J, et al. Among authors: feuerherd m. Front Immunol. 2022 Sep 7;13:889836. doi: 10.3389/fimmu.2022.889836. eCollection 2022. Front Immunol. 2022. PMID: 36159804 Free PMC article.
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.
Beck C, Ramanujam D, Vaccarello P, Widenmeyer F, Feuerherd M, Cheng CC, Bomhard A, Abikeeva T, Schädler J, Sperhake JP, Graw M, Safi S, Hoffmann H, Staab-Weijnitz CA, Rad R, Protzer U, Frischmuth T, Engelhardt S. Beck C, et al. Among authors: feuerherd m. Nat Commun. 2023 Jul 28;14(1):4564. doi: 10.1038/s41467-023-40185-1. Nat Commun. 2023. PMID: 37507393 Free PMC article.
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