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TCR-sequencing in cancer and autoimmunity: barcodes and beyond.
Pauken KE, Lagattuta KA, Lu BY, Lucca LE, Daud AI, Hafler DA, Kluger HM, Raychaudhuri S, Sharpe AH. Pauken KE, et al. Trends Immunol. 2022 Mar;43(3):180-194. doi: 10.1016/j.it.2022.01.002. Epub 2022 Jan 25. Trends Immunol. 2022. PMID: 35090787 Free PMC article. Review.
Overcoming T cell exhaustion in infection and cancer.
Pauken KE, Wherry EJ. Pauken KE, et al. Trends Immunol. 2015 Apr;36(4):265-76. doi: 10.1016/j.it.2015.02.008. Epub 2015 Mar 18. Trends Immunol. 2015. PMID: 25797516 Free PMC article. Review.
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.
Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJ, Klenerman P, Sharpe AH, Lauer GM, Haining WN. Gupta PK, et al. Among authors: pauken ke. PLoS Pathog. 2015 Oct 20;11(10):e1005177. doi: 10.1371/journal.ppat.1005177. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485519 Free PMC article.
The diverse functions of the PD1 inhibitory pathway.
Sharpe AH, Pauken KE. Sharpe AH, et al. Among authors: pauken ke. Nat Rev Immunol. 2018 Mar;18(3):153-167. doi: 10.1038/nri.2017.108. Epub 2017 Nov 13. Nat Rev Immunol. 2018. PMID: 28990585 Review.
Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage.
Johnnidis JB, Muroyama Y, Ngiow SF, Chen Z, Manne S, Cai Z, Song S, Platt JM, Schenkel JM, Abdel-Hakeem M, Beltra JC, Greenplate AR, Ali MA, Nzingha K, Giles JR, Harly C, Attanasio J, Pauken KE, Bengsch B, Paley MA, Tomov VT, Kurachi M, Vignali DAA, Sharpe AH, Reiner SL, Bhandoola A, Johnson FB, Wherry EJ. Johnnidis JB, et al. Among authors: pauken ke. Sci Immunol. 2021 Jan 15;6(55):eabe3702. doi: 10.1126/sciimmunol.abe3702. Sci Immunol. 2021. PMID: 33452106 Free PMC article.
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.
Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. Lo JA, et al. Among authors: pauken ke. Sci Transl Med. 2021 Feb 17;13(581):eabd8636. doi: 10.1126/scitranslmed.abd8636. Sci Transl Med. 2021. PMID: 33597266 Free PMC article.
40 results