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Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway.
Zhou J, Peacock TP, Brown JC, Goldhill DH, Elrefaey AME, Penrice-Randal R, Cowton VM, De Lorenzo G, Furnon W, Harvey WT, Kugathasan R, Frise R, Baillon L, Lassaunière R, Thakur N, Gallo G, Goldswain H, Donovan-Banfield I, Dong X, Randle NP, Sweeney F, Glynn MC, Quantrill JL, McKay PF, Patel AH, Palmarini M, Hiscox JA, Bailey D, Barclay WS. Zhou J, et al. Among authors: barclay ws. Cell Rep. 2022 Feb 8;38(6):110344. doi: 10.1016/j.celrep.2022.110344. Epub 2022 Jan 19. Cell Rep. 2022. PMID: 35093235 Free PMC article.
Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance.
Frise R, Bradley K, van Doremalen N, Galiano M, Elderfield RA, Stilwell P, Ashcroft JW, Fernandez-Alonso M, Miah S, Lackenby A, Roberts KL, Donnelly CA, Barclay WS. Frise R, et al. Among authors: barclay ws. Sci Rep. 2016 Jul 19;6:29793. doi: 10.1038/srep29793. Sci Rep. 2016. PMID: 27430528 Free PMC article.
Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics.
Peacock TP, Benton DJ, James J, Sadeyen JR, Chang P, Sealy JE, Bryant JE, Martin SR, Shelton H, Barclay WS, Iqbal M. Peacock TP, et al. Among authors: barclay ws. J Virol. 2017 Jun 26;91(14):e00218-17. doi: 10.1128/JVI.00218-17. Print 2017 Jul 15. J Virol. 2017. PMID: 28468875 Free PMC article.
The mechanism of resistance to favipiravir in influenza.
Goldhill DH, Te Velthuis AJW, Fletcher RA, Langat P, Zambon M, Lackenby A, Barclay WS. Goldhill DH, et al. Among authors: barclay ws. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11613-11618. doi: 10.1073/pnas.1811345115. Epub 2018 Oct 23. Proc Natl Acad Sci U S A. 2018. PMID: 30352857 Free PMC article.
284 results