Prakash A - Search Results

1

Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.

Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Among authors: prakash a. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.

2

The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C.

D'Arcy BM, Swingle MR, Papke CM, Abney KA, Bouska ES, Prakash A, Honkanen RE. D'Arcy BM, et al. Among authors: prakash a. Mol Cancer Ther. 2019 Mar;18(3):556-566. doi: 10.1158/1535-7163.MCT-17-1143. Epub 2019 Jan 24. Mol Cancer Ther. 2019. PMID: 30679389 Free PMC article.

3

The changing landscape of Lynch syndrome due to PMS2 mutations.

Blount J, Prakash A. Blount J, et al. Among authors: prakash a. Clin Genet. 2018 Jul;94(1):61-69. doi: 10.1111/cge.13205. Epub 2018 Mar 15. Clin Genet. 2018. PMID: 29286535 Free PMC article. Review.

4

Targeting phosphatases in cancer: suppression of many versus the ablation of one.

D'Arcy BM, Prakash A, Honkanen RE. D'Arcy BM, et al. Among authors: prakash a. Oncotarget. 2019 Nov 12;10(61):6543-6545. doi: 10.18632/oncotarget.27201. eCollection 2019 Nov 12. Oncotarget. 2019. PMID: 31762936 Free PMC article. No abstract available.

5

Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene.

D'Arcy BM, Blount J, Prakash A. D'Arcy BM, et al. Among authors: prakash a. Hum Mutat. 2019 Apr;40(4):458-471. doi: 10.1002/humu.23708. Epub 2019 Jan 30. Hum Mutat. 2019. PMID: 30653781 Free PMC article.

6

PMS2 variant results in loss of ATPase activity without compromising mismatch repair.

D'Arcy BM, Arrington J, Weisman J, McClellan SB, Vandana, Yang Z, Deivanayagam C, Blount J, Prakash A. D'Arcy BM, et al. Among authors: prakash a. Mol Genet Genomic Med. 2022 Feb 21;10(5):e1908. doi: 10.1002/mgg3.1908. Online ahead of print. Mol Genet Genomic Med. 2022. PMID: 35189042 Free PMC article.

7

Development of a Synthetic 3-ketosteroid Δ¹-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells.

D'Arcy BM, Swingle MR, Schambeau L, Pannell L, Prakash A, Honkanen RE. D'Arcy BM, et al. Among authors: prakash a. Sci Rep. 2019 Apr 12;9(1):5969. doi: 10.1038/s41598-019-42046-8. Sci Rep. 2019. PMID: 30979909 Free PMC article.

8

Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair.

Thompson MK, Sobol RW, Prakash A. Thompson MK, et al. Among authors: prakash a. Biology (Basel). 2021 Jun 14;10(6):530. doi: 10.3390/biology10060530. Biology (Basel). 2021. PMID: 34198612 Free PMC article. Review.

9

Editorial: Regulatory networks in genome stability pathways.

Ashton NW, Prakash A, Moiseeva TN. Ashton NW, et al. Among authors: prakash a. Front Genet. 2023 Mar 14;14:1171136. doi: 10.3389/fgene.2023.1171136. eCollection 2023. Front Genet. 2023. PMID: 36999052 Free PMC article. No abstract available.

10

DNA damage related crosstalk between the nucleus and mitochondria.

Saki M, Prakash A. Saki M, et al. Among authors: prakash a. Free Radic Biol Med. 2017 Jun;107:216-227. doi: 10.1016/j.freeradbiomed.2016.11.050. Epub 2016 Nov 30. Free Radic Biol Med. 2017. PMID: 27915046 Free PMC article. Review.

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