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Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4+ T Cell Counts and Body Weight.
Swainson LA, Ahn H, Pajanirassa P, Khetarpal V, Deleage C, Estes JD, Hunt PW, Munoz-Sanjuan I, McCune JM. Swainson LA, et al. Among authors: mccune jm. J Immunol. 2019 Aug 15;203(4):899-910. doi: 10.4049/jimmunol.1801649. Epub 2019 Jul 8. J Immunol. 2019. PMID: 31285277 Free PMC article.
TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. Rutishauser RL, et al. Among authors: mccune jm. JCI Insight. 2021 Feb 8;6(3):e136648. doi: 10.1172/jci.insight.136648. JCI Insight. 2021. PMID: 33351785 Free PMC article.
HIV-induced changes in T cell signaling pathways.
Schweneker M, Favre D, Martin JN, Deeks SG, McCune JM. Schweneker M, et al. Among authors: mccune jm. J Immunol. 2008 May 15;180(10):6490-500. doi: 10.4049/jimmunol.180.10.6490. J Immunol. 2008. PMID: 18453567 Free PMC article.
Immunosenescence and HIV.
Deeks SG, Verdin E, McCune JM. Deeks SG, et al. Among authors: mccune jm. Curr Opin Immunol. 2012 Aug;24(4):501-6. doi: 10.1016/j.coi.2012.05.004. Epub 2012 Jun 2. Curr Opin Immunol. 2012. PMID: 22658763 Review.
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase.
Dunham RM, Gordon SN, Vaccari M, Piatak M, Huang Y, Deeks SG, Lifson J, Franchini G, McCune JM. Dunham RM, et al. Among authors: mccune jm. AIDS Res Hum Retroviruses. 2013 Feb;29(2):207-14. doi: 10.1089/AID.2012.0162. Epub 2012 Oct 9. AIDS Res Hum Retroviruses. 2013. PMID: 22924680 Free PMC article.
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Jain V, et al. Among authors: mccune jm. J Infect Dis. 2013 Oct 15;208(8):1202-11. doi: 10.1093/infdis/jit311. Epub 2013 Jul 12. J Infect Dis. 2013. PMID: 23852127 Free PMC article.
Discordance between peripheral and colonic markers of inflammation during suppressive ART.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. Dunham RM, et al. Among authors: mccune jm. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):133-41. doi: 10.1097/01.qai.0000437172.08127.0b. J Acquir Immune Defic Syndr. 2014. PMID: 24121758 Free PMC article.
264 results