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Targeting TGF-β for treatment of osteogenesis imperfecta.
Song IW, Nagamani SC, Nguyen D, Grafe I, Sutton VR, Gannon FH, Munivez E, Jiang MM, Tran A, Wallace M, Esposito P, Musaad S, Strudthoff E, McGuire S, Thornton M, Shenava V, Rosenfeld S, Huang S, Shypailo R, Orwoll E, Lee B. Song IW, et al. Among authors: huang s. J Clin Invest. 2022 Apr 1;132(7):e152571. doi: 10.1172/JCI152571. J Clin Invest. 2022. PMID: 35113812 Free PMC article. Clinical Trial.
Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer.
Sethunath V, Hu H, De Angelis C, Veeraraghavan J, Qin L, Wang N, Simon LM, Wang T, Fu X, Nardone A, Pereira R, Nanda S, Griffith OL, Tsimelzon A, Shaw C, Chamness GC, Reis-Filho JS, Weigelt B, Heiser LM, Hilsenbeck SG, Huang S, Rimawi MF, Gray JW, Osborne CK, Schiff R. Sethunath V, et al. Among authors: huang s. Mol Cancer Res. 2019 Nov;17(11):2318-2330. doi: 10.1158/1541-7786.MCR-19-0756. Epub 2019 Aug 16. Mol Cancer Res. 2019. PMID: 31420371 Free PMC article.
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.
Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG. Jayaraman P, et al. Among authors: huang s. Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018. Oncoimmunology. 2018. PMID: 30288358 Free PMC article.
High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array.
Wang X, Shi Z, Lu HY, Kim JJ, Bu W, Villalobos JA, Perera DN, Jung SY, Wang T, Grimm SL, Taylor BC, Rajapakshe K, Park H, Wulfkuhle J, Young NL, Li Y, Coarfa C, Edwards DP, Huang S. Wang X, et al. Among authors: huang s. J Proteomics. 2022 Jun 30;262:104596. doi: 10.1016/j.jprot.2022.104596. Epub 2022 Apr 27. J Proteomics. 2022. PMID: 35489683 Free PMC article.
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