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Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages.
Genes Immun. 2022 Apr;23(2):73-84. doi: 10.1038/s41435-022-00164-w. Epub 2022 Feb 3.
Genes Immun. 2022.
PMID: 35115664
Free PMC article.
Recent and future perspectives on engineering interferons and other cytokines as therapeutics.
Aung T, Grubbe WS, Nusbaum RJ, Mendoza JL.
Aung T, et al. Among authors: grubbe ws.
Trends Biochem Sci. 2023 Mar;48(3):259-273. doi: 10.1016/j.tibs.2022.09.005. Epub 2022 Oct 11.
Trends Biochem Sci. 2023.
PMID: 36241490
Free PMC article.
Review.
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Cell-free styrene biosynthesis at high titers.
Grubbe WS, Rasor BJ, Krüger A, Jewett MC, Karim AS.
Grubbe WS, et al.
Metab Eng. 2020 Sep;61:89-95. doi: 10.1016/j.ymben.2020.05.009. Epub 2020 Jun 2.
Metab Eng. 2020.
PMID: 32502620
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In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design.
Karim AS, Dudley QM, Juminaga A, Yuan Y, Crowe SA, Heggestad JT, Garg S, Abdalla T, Grubbe WS, Rasor BJ, Coar DN, Torculas M, Krein M, Liew FE, Quattlebaum A, Jensen RO, Stuart JA, Simpson SD, Köpke M, Jewett MC.
Karim AS, et al. Among authors: grubbe ws.
Nat Chem Biol. 2020 Aug;16(8):912-919. doi: 10.1038/s41589-020-0559-0. Epub 2020 Jun 15.
Nat Chem Biol. 2020.
PMID: 32541965
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Molecular analysis of the type III interferon complex and its applications in protein engineering.
Grubbe WS, Byléhn F, Alvarado W, de Pablo JJ, Mendoza JL.
Grubbe WS, et al.
Biophys J. 2023 Nov 7;122(21):4254-4263. doi: 10.1016/j.bpj.2023.09.021. Epub 2023 Oct 4.
Biophys J. 2023.
PMID: 37794680
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