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Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors.
Jeschke J, Collignon E, Al Wardi C, Krayem M, Bizet M, Jia Y, Garaud S, Wimana Z, Calonne E, Hassabi B, Morandini R, Deplus R, Putmans P, Dube G, Singh NK, Koch A, Shostak K, Rizzotto L, Ross RL, Desmedt C, Bareche Y, Rothé F, Lehmann-Che J, Duterque-Coquillaud M, Leroy X, Menschaert G, Teixeira L, Guo M, Limbach PA, Close P, Chariot A, Leucci E, Ghanem G, Yuan BF, Willard-Gallo K, Sotiriou C, Marine JC, Fuks F. Jeschke J, et al. Among authors: menschaert g. Nat Cancer. 2021 Jun;2(6):611-628. doi: 10.1038/s43018-021-00223-7. Epub 2021 Jun 23. Nat Cancer. 2021. PMID: 35121941 Free PMC article.
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation.
Lan J, Rajan N, Bizet M, Penning A, Singh NK, Guallar D, Calonne E, Li Greci A, Bonvin E, Deplus R, Hsu PJ, Nachtergaele S, Ma C, Song R, Fuentes-Iglesias A, Hassabi B, Putmans P, Mies F, Menschaert G, Wong JJL, Wang J, Fidalgo M, Yuan B, Fuks F. Lan J, et al. Among authors: menschaert g. Nat Commun. 2020 Oct 2;11(1):4956. doi: 10.1038/s41467-020-18729-6. Nat Commun. 2020. PMID: 33009383 Free PMC article.
A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites.
Koch A, Gawron D, Steyaert S, Ndah E, Crappé J, De Keulenaer S, De Meester E, Ma M, Shen B, Gevaert K, Van Criekinge W, Van Damme P, Menschaert G. Koch A, et al. Among authors: menschaert g. Proteomics. 2014 Dec;14(23-24):2688-98. doi: 10.1002/pmic.201400180. Epub 2014 Oct 2. Proteomics. 2014. PMID: 25156699 Free PMC article.
Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events.
Menschaert G, Van Criekinge W, Notelaers T, Koch A, Crappé J, Gevaert K, Van Damme P. Menschaert G, et al. Mol Cell Proteomics. 2013 Jul;12(7):1780-90. doi: 10.1074/mcp.M113.027540. Epub 2013 Feb 21. Mol Cell Proteomics. 2013. PMID: 23429522 Free PMC article.
PROTEOFORMER: deep proteome coverage through ribosome profiling and MS integration.
Crappé J, Ndah E, Koch A, Steyaert S, Gawron D, De Keulenaer S, De Meester E, De Meyer T, Van Criekinge W, Van Damme P, Menschaert G. Crappé J, et al. Among authors: menschaert g. Nucleic Acids Res. 2015 Mar 11;43(5):e29. doi: 10.1093/nar/gku1283. Epub 2014 Dec 15. Nucleic Acids Res. 2015. PMID: 25510491 Free PMC article.
Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation.
Gachet S, El-Chaar T, Avran D, Genesca E, Catez F, Quentin S, Delord M, Thérizols G, Briot D, Meunier G, Hernandez L, Pla M, Smits WK, Buijs-Gladdines JG, Van Loocke W, Menschaert G, André-Schmutz I, Taghon T, Van Vlierberghe P, Meijerink JP, Baruchel A, Dombret H, Clappier E, Diaz JJ, Gazin C, de Thé H, Sigaux F, Soulier J. Gachet S, et al. Among authors: menschaert g. Cancer Discov. 2018 Dec;8(12):1614-1631. doi: 10.1158/2159-8290.CD-17-0831. Epub 2018 Sep 28. Cancer Discov. 2018. PMID: 30266814
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly.
Zhang S, Reljić B, Liang C, Kerouanton B, Francisco JC, Peh JH, Mary C, Jagannathan NS, Olexiouk V, Tang C, Fidelito G, Nama S, Cheng RK, Wee CL, Wang LC, Duek Roggli P, Sampath P, Lane L, Petretto E, Sobota RM, Jesuthasan S, Tucker-Kellogg L, Reversade B, Menschaert G, Sun L, Stroud DA, Ho L. Zhang S, et al. Among authors: menschaert g. Nat Commun. 2020 Mar 11;11(1):1312. doi: 10.1038/s41467-020-14999-2. Nat Commun. 2020. PMID: 32161263 Free PMC article.
66 results