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Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism.
Bills CJ, Xia H, Chen JY, Yeung J, Kalveram BK, Walker D, Xie X, Shi PY. Bills CJ, et al. Among authors: kalveram bk. Emerg Microbes Infect. 2023 Dec;12(1):2209208. doi: 10.1080/22221751.2023.2209208. Emerg Microbes Infect. 2023. PMID: 37114433 Free PMC article.
Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Ku Z, Xie X, Lin J, Gao P, Wu B, El Sahili A, Su H, Liu Y, Ye X, Tan EY, Li X, Fan X, Goh BC, Xiong W, Boyd H, Muruato AE, Deng H, Xia H, Zou J, Kalveram BK, Menachery VD, Zhang N, Lescar J, Shi PY, An Z. Ku Z, et al. Among authors: kalveram bk. Nat Commun. 2022 Sep 22;13(1):5552. doi: 10.1038/s41467-022-33284-y. Nat Commun. 2022. PMID: 36138032 Free PMC article.
Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Ku Z, Xie X, Lin J, Gao P, El Sahili A, Su H, Liu Y, Ye X, Li X, Fan X, Goh BC, Xiong W, Boyd H, Muruato AE, Deng H, Xia H, Jing Z, Kalveram BK, Menachery VD, Zhang N, Lescar J, Shi PY, An Z. Ku Z, et al. Among authors: kalveram bk. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478504. doi: 10.1101/2022.02.01.478504. bioRxiv. 2022. PMID: 35132410 Free PMC article. Updated. Preprint.
Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts.
Warmbrod KL, Patterson EI, Kautz TF, Stanton A, Rockx-Brouwer D, Kalveram BK, Khanipov K, Thangamani S, Fofanov Y, Forrester NL. Warmbrod KL, et al. Among authors: kalveram bk. PLoS Pathog. 2019 Apr 4;15(4):e1007610. doi: 10.1371/journal.ppat.1007610. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30947291 Free PMC article.