Bushweller JH - Search Results

1

KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer.

Kim KB, Kabra A, Kim DW, Xue Y, Huang Y, Hou PC, Zhou Y, Miranda LJ, Park JI, Shi X, Bender TP, Bushweller JH, Park KS. Kim KB, et al. Among authors: bushweller jh. Sci Adv. 2022 Feb 18;8(7):eabl4618. doi: 10.1126/sciadv.abl4618. Epub 2022 Feb 16. Sci Adv. 2022. PMID: 35171684 Free PMC article.

2

Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta.

Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, Brown ML, Bushweller JH. Gorczynski MJ, et al. Among authors: bushweller jh. Chem Biol. 2007 Oct;14(10):1186-97. doi: 10.1016/j.chembiol.2007.09.006. Chem Biol. 2007. PMID: 17961830

3

NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.

Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. Zhou Y, et al. Among authors: bushweller jh. Mol Cell. 2008 Sep 26;31(6):896-908. doi: 10.1016/j.molcel.2008.08.028. Mol Cell. 2008. PMID: 18922471 Free PMC article.

4

Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.

Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH. Illendula A, et al. Among authors: bushweller jh. Science. 2015 Feb 13;347(6223):779-84. doi: 10.1126/science.aaa0314. Science. 2015. PMID: 25678665 Free PMC article.

5

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.

Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH. Illendula A, et al. Among authors: bushweller jh. EBioMedicine. 2016 Jun;8:117-131. doi: 10.1016/j.ebiom.2016.04.032. Epub 2016 Apr 29. EBioMedicine. 2016. PMID: 27428424 Free PMC article.

6

A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells.

Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH. Oo ZM, et al. Among authors: bushweller jh. Leuk Lymphoma. 2018 Sep;59(9):2188-2200. doi: 10.1080/10428194.2017.1410882. Epub 2017 Dec 18. Leuk Lymphoma. 2018. PMID: 29249175 Free PMC article.

7

Solution structure and elevator mechanism of the membrane electron transporter CcdA.

Zhou Y, Bushweller JH. Zhou Y, et al. Among authors: bushweller jh. Nat Struct Mol Biol. 2018 Feb;25(2):163-169. doi: 10.1038/s41594-018-0022-z. Epub 2018 Jan 29. Nat Struct Mol Biol. 2018. PMID: 29379172 Free PMC article.

8

The Intrinsically Disordered Proteins MLLT3 (AF9) and MLLT1 (ENL) - Multimodal Transcriptional Switches With Roles in Normal Hematopoiesis, MLL Fusion Leukemia, and Kidney Cancer.

Kabra A, Bushweller J. Kabra A, et al. J Mol Biol. 2022 Jan 15;434(1):167117. doi: 10.1016/j.jmb.2021.167117. Epub 2021 Jun 23. J Mol Biol. 2022. PMID: 34174329 Free PMC article. Review.

9

Small-Molecule Inhibitors of the MLL1 CXXC Domain, an Epigenetic Reader of DNA Methylation.

Kalmode HP, Podsiadly I, Kabra A, Boulton A, Reddy P, Gao Y, Li C, Bushweller JH. Kalmode HP, et al. Among authors: bushweller jh. ACS Med Chem Lett. 2022 Jul 7;13(8):1363-1369. doi: 10.1021/acsmedchemlett.2c00198. eCollection 2022 Aug 11. ACS Med Chem Lett. 2022. PMID: 35978680 Free PMC article.

10

Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.

Park S, Chen W, Cierpicki T, Tonelli M, Cai X, Speck NA, Bushweller JH. Park S, et al. Among authors: bushweller jh. Blood. 2009 Apr 9;113(15):3558-67. doi: 10.1182/blood-2008-06-161307. Epub 2009 Feb 9. Blood. 2009. PMID: 19204326 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

103 results

Search Page