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Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains.
Chen C, Saville JW, Marti MM, Schäfer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W. Chen C, et al. Among authors: schafer a. bioRxiv [Preprint]. 2022 Feb 24:2022.02.18.481058. doi: 10.1101/2022.02.18.481058. bioRxiv. 2022. PMID: 35194603 Free PMC article. Updated. Preprint.
Systems approaches to Coronavirus pathogenesis.
Schäfer A, Baric RS, Ferris MT. Schäfer A, et al. Curr Opin Virol. 2014 Jun;6:61-9. doi: 10.1016/j.coviro.2014.04.007. Epub 2014 May 17. Curr Opin Virol. 2014. PMID: 24842079 Free PMC article. Review.
The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus.
McDermott JE, Mitchell HD, Gralinski LE, Eisfeld AJ, Josset L, Bankhead A 3rd, Neumann G, Tilton SC, Schäfer A, Li C, Fan S, McWeeney S, Baric RS, Katze MG, Waters KM. McDermott JE, et al. Among authors: schafer a. BMC Syst Biol. 2016 Sep 23;10(1):93. doi: 10.1186/s12918-016-0336-6. BMC Syst Biol. 2016. PMID: 27663205 Free PMC article.
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV.
Sheahan TP, Sims AC, Leist SR, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, Cihlar T, Jordan R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: schafer a. Nat Commun. 2020 Jan 10;11(1):222. doi: 10.1038/s41467-019-13940-6. Nat Commun. 2020. PMID: 31924756 Free PMC article.
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH 3rd, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: schafer a. Sci Transl Med. 2020 Apr 29;12(541):eabb5883. doi: 10.1126/scitranslmed.abb5883. Epub 2020 Apr 6. Sci Transl Med. 2020. PMID: 32253226 Free PMC article.
1,677 results