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Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis.
Antunes KH, Stein RT, Franceschina C, da Silva EF, de Freitas DN, Silveira J, Mocellin M, Leitão L, Fachi JL, Pral LP, Gonzalez A, Oliveira S, Duarte L, Cassão G, Gonçalves JIB, Reis TM, Abbadi BL, Dornelles M, Sperotto NDM, Rigo M, Rodrigues H, Jones M, Epifanio M, Guima S, Setubal JC, Jorge TR, Mansur DS, Mayer FQ, Varela APM, Bizarro CV, Machado P, Basso LA, Polack FP, Custovic A, Vinolo MAR, de Souza APD. Antunes KH, et al. Among authors: abbadi bl. EBioMedicine. 2022 Mar;77:103891. doi: 10.1016/j.ebiom.2022.103891. Epub 2022 Feb 24. EBioMedicine. 2022. PMID: 35220042 Free PMC article.
2-(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains.
Pissinate K, Villela AD, Rodrigues-Junior V, Giacobbo BC, Grams ES, Abbadi BL, Trindade RV, Roesler Nery L, Bonan CD, Back DF, Campos MM, Basso LA, Santos DS, Machado P. Pissinate K, et al. Among authors: abbadi bl. ACS Med Chem Lett. 2016 Jan 11;7(3):235-9. doi: 10.1021/acsmedchemlett.5b00324. eCollection 2016 Mar 10. ACS Med Chem Lett. 2016. PMID: 26985307 Free PMC article.
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection.
Rodrigues-Junior VS, Villela AD, Gonçalves RS, Abbadi BL, Trindade RV, López-Gavín A, Tudó G, González-Martín J, Basso LA, de Souza MV, Campos MM, Santos DS. Rodrigues-Junior VS, et al. Among authors: abbadi bl. Int J Antimicrob Agents. 2016 Aug;48(2):203-7. doi: 10.1016/j.ijantimicag.2016.04.029. Epub 2016 Jun 7. Int J Antimicrob Agents. 2016. PMID: 27364701
New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis.
Giacobbo BC, Pissinate K, Rodrigues-Junior V, Villela AD, Grams ES, Abbadi BL, Subtil FT, Sperotto N, Trindade RV, Back DF, Campos MM, Basso LA, Machado P, Santos DS. Giacobbo BC, et al. Among authors: abbadi bl. Eur J Med Chem. 2017 Jan 27;126:491-501. doi: 10.1016/j.ejmech.2016.11.048. Epub 2016 Nov 23. Eur J Med Chem. 2017. PMID: 27914363
Activity of 2-(quinolin-4-yloxy)acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing.
Subtil FT, Villela AD, Abbadi BL, Rodrigues-Junior VS, Bizarro CV, Timmers LFSM, de Souza ON, Pissinate K, Machado P, López-Gavín A, Tudó G, González-Martín J, Basso LA, Santos DS. Subtil FT, et al. Among authors: abbadi bl. Int J Antimicrob Agents. 2018 Mar;51(3):378-384. doi: 10.1016/j.ijantimicag.2017.08.023. Epub 2017 Aug 23. Int J Antimicrob Agents. 2018. PMID: 28843821 Free article.
Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.
Laborde J, Deraeve C, de Mesquita Vieira FG, Sournia-Saquet A, Rechignat L, Villela AD, Abbadi BL, Macchi FS, Pissinate K, Bizarro CV, Machado P, Basso LA, Pratviel G, de França Lopes LG, Sousa EHS, Bernardes-Génisson V. Laborde J, et al. Among authors: abbadi bl. J Inorg Biochem. 2018 Feb;179:71-81. doi: 10.1016/j.jinorgbio.2017.11.013. Epub 2017 Nov 21. J Inorg Biochem. 2018. PMID: 29175704
28 results