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Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
Arredondo C, Cefaliello C, Dyrda A, Jury N, Martinez P, Díaz I, Amaro A, Tran H, Morales D, Pertusa M, Stoica L, Fritz E, Corvalán D, Abarzúa S, Méndez-Ruette M, Fernández P, Rojas F, Kumar MS, Aguilar R, Almeida S, Weiss A, Bustos FJ, González-Nilo F, Otero C, Tevy MF, Bosco DA, Sáez JC, Kähne T, Gao FB, Berry JD, Nicholson K, Sena-Esteves M, Madrid R, Varela D, Montecino M, Brown RH, van Zundert B. Arredondo C, et al. Among authors: gonzalez nilo f. Neuron. 2022 May 18;110(10):1656-1670.e12. doi: 10.1016/j.neuron.2022.02.010. Epub 2022 Mar 10. Neuron. 2022. PMID: 35276083 Free PMC article.
A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII.
López X, Palacios-Prado N, Güiza J, Escamilla R, Fernández P, Vega JL, Rojas M, Marquez-Miranda V, Chamorro E, Cárdenas AM, Maldifassi MC, Martínez AD, Duarte Y, González-Nilo FD, Sáez JC. López X, et al. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2108967118. doi: 10.1073/pnas.2108967118. Proc Natl Acad Sci U S A. 2021. PMID: 34301850 Free PMC article.
Unnexins: Homologs of innexin proteins in Trypanosomatidae parasites.
Güiza J, García A, Arriagada J, Gutiérrez C, González J, Márquez-Miranda V, Alegría-Arcos M, Duarte Y, Rojas M, González-Nilo F, Sáez JC, Vega JL. Güiza J, et al. Among authors: gonzalez nilo f. J Cell Physiol. 2022 Feb;237(2):1547-1560. doi: 10.1002/jcp.30626. Epub 2021 Nov 15. J Cell Physiol. 2022. PMID: 34779505
Endogenous pannexin1 channels form functional intercellular cell-cell channels with characteristic voltage-dependent properties.
Palacios-Prado N, Soto PA, López X, Choi EJ, Marquez-Miranda V, Rojas M, Duarte Y, Lee J, González-Nilo FD, Sáez JC. Palacios-Prado N, et al. Among authors: gonzalez nilo fd. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2202104119. doi: 10.1073/pnas.2202104119. Epub 2022 Apr 29. Proc Natl Acad Sci U S A. 2022. PMID: 35486697 Free PMC article.
Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines.
Peñaloza JP, Márquez-Miranda V, Cabaña-Brunod M, Reyes-Ramírez R, Llancalahuen FM, Vilos C, Maldonado-Biermann F, Velásquez LA, Fuentes JA, González-Nilo FD, Rodríguez-Díaz M, Otero C. Peñaloza JP, et al. J Nanobiotechnology. 2017 Jan 3;15(1):1. doi: 10.1186/s12951-016-0241-6. J Nanobiotechnology. 2017. PMID: 28049488 Free PMC article.
Inorganic polyphosphate as an energy source in tumorigenesis.
Boyineni J, Sredni ST, Margaryan NV, Demirkhanyan L, Tye M, Johnson R, Gonzalez-Nilo F, Hendrix MJC, Pavlov E, Soares MB, Zakharian E, Malchenko S. Boyineni J, et al. Oncotarget. 2020 Dec 15;11(50):4613-4624. doi: 10.18632/oncotarget.27838. eCollection 2020 Dec 15. Oncotarget. 2020. PMID: 33400735 Free PMC article.
121 results