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Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
Arredondo C, Cefaliello C, Dyrda A, Jury N, Martinez P, Díaz I, Amaro A, Tran H, Morales D, Pertusa M, Stoica L, Fritz E, Corvalán D, Abarzúa S, Méndez-Ruette M, Fernández P, Rojas F, Kumar MS, Aguilar R, Almeida S, Weiss A, Bustos FJ, González-Nilo F, Otero C, Tevy MF, Bosco DA, Sáez JC, Kähne T, Gao FB, Berry JD, Nicholson K, Sena-Esteves M, Madrid R, Varela D, Montecino M, Brown RH, van Zundert B. Arredondo C, et al. Among authors: morales d. Neuron. 2022 May 18;110(10):1656-1670.e12. doi: 10.1016/j.neuron.2022.02.010. Epub 2022 Mar 10. Neuron. 2022. PMID: 35276083 Free PMC article.
EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion.
Blanco C, Morales D, Mogollones I, Vergara-Jaque A, Vargas C, Álvarez A, Riquelme D, Leiva-Salcedo E, González W, Morales D, Maureira D, Aldunate I, Cáceres M, Varela D, Cerda O. Blanco C, et al. Among authors: morales d. FASEB J. 2019 Aug;33(8):9434-9452. doi: 10.1096/fj.201900136R. Epub 2019 May 21. FASEB J. 2019. PMID: 31112396
Finally, we demonstrated that the expression of a soluble fragment containing the EB binding motif of TRPM4 reduces the plasma membrane expression of the channel and affects TRPM4-dependent focal adhesion disassembly and cell invasion processes.-Blanco, C., Morales, D …
Finally, we demonstrated that the expression of a soluble fragment containing the EB binding motif of TRPM4 reduces the plasma membrane expr …
KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis.
Rivas J, Díaz N, Silva I, Morales D, Lavanderos B, Álvarez A, Saldías MP, Pulgar E, Cruz P, Maureira D, Flores G, Colombo A, Blanco C, Contreras HR, Jaña F, Gallegos I, Concha ML, Vergara-Jaque A, Poblete H, González W, Varela D, Trimmer JS, Cáceres M, Cerda O. Rivas J, et al. Among authors: morales d. FASEB J. 2020 Jun;34(6):7847-7865. doi: 10.1096/fj.201901195RRR. Epub 2020 Apr 17. FASEB J. 2020. PMID: 32301552
FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway.
Urra FA, Muñoz F, Córdova-Delgado M, Ramírez MP, Peña-Ahumada B, Rios M, Cruz P, Ahumada-Castro U, Bustos G, Silva-Pavez E, Pulgar R, Morales D, Varela D, Millas-Vargas JP, Retamal E, Ramírez-Rodríguez O, Pessoa-Mahana H, Pavani M, Ferreira J, Cárdenas C, Araya-Maturana R. Urra FA, et al. Among authors: morales d. Sci Rep. 2018 Sep 4;8(1):13190. doi: 10.1038/s41598-018-31367-9. Sci Rep. 2018. PMID: 30181620 Free PMC article.
Levels of Small Extracellular Vesicles Containing hERG-1 and Hsp47 as Potential Biomarkers for Cardiovascular Diseases.
Osorio LA, Lozano M, Soto P, Moreno-Hidalgo V, Arévalo-Gil A, Ramírez-Balaguera A, Hevia D, Cifuentes J, Hidalgo Y, Alcayaga-Miranda F, Pasten C, Morales D, Varela D, Urquidi C, Iturriaga A, Rivera-Palma A, Larrea-Gómez R, Irarrázabal CE. Osorio LA, et al. Among authors: morales d. Int J Mol Sci. 2024 Apr 30;25(9):4913. doi: 10.3390/ijms25094913. Int J Mol Sci. 2024. PMID: 38732154 Free PMC article.
Predicting Stroke For Pediatric Patients Supported With Ventricular Assist Devices:A PEDIMACS Report.
Ashfaq A, Lorts A, Rosenthal D, Adachi I, Rossano J, Davies R, Simpson KE, Maeda K, Wisotzkey B, Koehl D, Cantor RS, Jacobs JP, Peng D, Kirklin JK, Morales DLS. Ashfaq A, et al. Among authors: morales dls. Ann Thorac Surg. 2024 May 25:S0003-4975(24)00386-2. doi: 10.1016/j.athoracsur.2024.05.009. Online ahead of print. Ann Thorac Surg. 2024. PMID: 38802036
1,149 results