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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses.
Mittler E, Wec AZ, Tynell J, Guardado-Calvo P, Wigren-Byström J, Polanco LC, O'Brien CM, Slough MM, Abelson DM, Serris A, Sakharkar M, Pehau-Arnaudet G, Bakken RR, Geoghegan JC, Jangra RK, Keller M, Zeitlin L, Vapalahti O, Ulrich RG, Bornholdt ZA, Ahlm C, Rey FA, Dye JM, Bradfute SB, Strandin T, Herbert AS, Forsell MNE, Walker LM, Chandran K. Mittler E, et al. Among authors: dye jm. Sci Transl Med. 2022 Mar 16;14(636):eabl5399. doi: 10.1126/scitranslmed.abl5399. Epub 2022 Mar 16. Sci Transl Med. 2022. PMID: 35294259 Free PMC article.
Filovirus vaccines.
Bradfute SB, Dye JM Jr, Bavari S. Bradfute SB, et al. Among authors: dye jm jr. Hum Vaccin. 2011 Jun;7(6):701-11. doi: 10.4161/hv.7.6.15398. Epub 2011 Jun 1. Hum Vaccin. 2011. PMID: 21519188 Free PMC article. Review.
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Carette JE, et al. Among authors: dye jm. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. Nature. 2011. PMID: 21866103 Free PMC article.
A shared structural solution for neutralizing ebolaviruses.
Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. Dias JM, et al. Among authors: dye jm. Nat Struct Mol Biol. 2011 Nov 20;18(12):1424-7. doi: 10.1038/nsmb.2150. Nat Struct Mol Biol. 2011. PMID: 22101933 Free PMC article.
Ebola virus entry requires the host-programmed recognition of an intracellular receptor.
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Miller EH, et al. Among authors: dye jm. EMBO J. 2012 Apr 18;31(8):1947-60. doi: 10.1038/emboj.2012.53. Epub 2012 Mar 6. EMBO J. 2012. PMID: 22395071 Free PMC article.
Structural basis for differential neutralization of ebolaviruses.
Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL Jr, Chandran K, Dye JM, Saphire EO. Bale S, et al. Among authors: dye jm. Viruses. 2012 Apr;4(4):447-70. doi: 10.3390/v4040447. Epub 2012 Apr 5. Viruses. 2012. PMID: 22590681 Free PMC article. Review.
Venezuelan equine encephalitis virus replicon particle vaccine protects nonhuman primates from intramuscular and aerosol challenge with ebolavirus.
Herbert AS, Kuehne AI, Barth JF, Ortiz RA, Nichols DK, Zak SE, Stonier SW, Muhammad MA, Bakken RR, Prugar LI, Olinger GG, Groebner JL, Lee JS, Pratt WD, Custer M, Kamrud KI, Smith JF, Hart MK, Dye JM. Herbert AS, et al. Among authors: dye jm. J Virol. 2013 May;87(9):4952-64. doi: 10.1128/JVI.03361-12. Epub 2013 Feb 13. J Virol. 2013. PMID: 23408633 Free PMC article.
157 results