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Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy.
Varco-Merth BD, Brantley W, Marenco A, Duell DD, Fachko DN, Richardson B, Busman-Sahay K, Shao D, Flores W, Engelman K, Fukazawa Y, Wong SW, Skalsky RL, Smedley J, Axthelm MK, Lifson JD, Estes JD, Edlefsen PT, Picker LJ, Cameron CM, Henrich TJ, Okoye AA. Varco-Merth BD, et al. Among authors: picker lj. J Clin Invest. 2022 May 16;132(10):e156063. doi: 10.1172/JCI156063. J Clin Invest. 2022. PMID: 35316218 Free PMC article.
The CD4(+) T cell response to HIV-1.
Picker LJ, Maino VC. Picker LJ, et al. Curr Opin Immunol. 2000 Aug;12(4):381-6. doi: 10.1016/s0952-7915(00)00104-7. Curr Opin Immunol. 2000. PMID: 10899031 Review.
Development and homeostasis of T cell memory in rhesus macaque.
Pitcher CJ, Hagen SI, Walker JM, Lum R, Mitchell BL, Maino VC, Axthelm MK, Picker LJ. Pitcher CJ, et al. Among authors: picker lj. J Immunol. 2002 Jan 1;168(1):29-43. doi: 10.4049/jimmunol.168.1.29. J Immunol. 2002. PMID: 11751943
Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239.
Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, Wang C, Allison DB, Watkins DI. Horton H, et al. Among authors: picker lj. J Virol. 2002 Jul;76(14):7187-202. doi: 10.1128/jvi.76.14.7187-7202.2002. J Virol. 2002. PMID: 12072518 Free PMC article. Clinical Trial.
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M Jr, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ. Okoye A, et al. Among authors: picker lj. J Exp Med. 2007 Sep 3;204(9):2171-85. doi: 10.1084/jem.20070567. Epub 2007 Aug 27. J Exp Med. 2007. PMID: 17724130 Free PMC article.
251 results