Levine PM - Search Results

1

Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation".

Levine PM, Craven TW, Li X, Balana AT, Bird GH, Godes M, Salveson PJ, Erickson PW, Lamb M, Ahlrichs M, Murphy M, Ogohara C, Said MY, Walensky LD, Pratt MR, Baker D. Levine PM, et al. ACS Chem Biol. 2022 Apr 15;17(4):804-809. doi: 10.1021/acschembio.2c00075. Epub 2022 Mar 23. ACS Chem Biol. 2022. PMID: 35319882 Free PMC article.

2

Androgen receptor antagonism by divalent ethisterone conjugates in castrate-resistant prostate cancer cells.

Levine PM, Lee E, Greenfield A, Bonneau R, Logan SK, Garabedian MJ, Kirshenbaum K. Levine PM, et al. ACS Chem Biol. 2012 Oct 19;7(10):1693-701. doi: 10.1021/cb300332w. Epub 2012 Aug 7. ACS Chem Biol. 2012. PMID: 22871957 Free PMC article.

3

Chemoselective fragment condensation between peptide and peptidomimetic oligomers.

Levine PM, Craven TW, Bonneau R, Kirshenbaum K. Levine PM, et al. Org Biomol Chem. 2013 Jul 7;11(25):4142-6. doi: 10.1039/c3ob40606g. Org Biomol Chem. 2013. PMID: 23715215

4

Semisynthesis of peptoid-protein hybrids by chemical ligation at serine.

Levine PM, Craven TW, Bonneau R, Kirshenbaum K. Levine PM, et al. Org Lett. 2014 Jan 17;16(2):512-5. doi: 10.1021/ol4033978. Epub 2014 Jan 3. Org Lett. 2014. PMID: 24393000

5

Intrinsic bioconjugation for site-specific protein PEGylation at N-terminal serine.

Levine PM, Craven TW, Bonneau R, Kirshenbaum K. Levine PM, et al. Chem Commun (Camb). 2014 Jul 4;50(52):6909-12. doi: 10.1039/c4cc01928h. Chem Commun (Camb). 2014. PMID: 24840103

6

O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding.

Lewis YE, Galesic A, Levine PM, De Leon CA, Lamiri N, Brennan CK, Pratt MR. Lewis YE, et al. Among authors: levine pm. ACS Chem Biol. 2017 Apr 21;12(4):1020-1027. doi: 10.1021/acschembio.7b00113. Epub 2017 Feb 22. ACS Chem Biol. 2017. PMID: 28195695 Free PMC article.

7

O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein.

Levine PM, De Leon CA, Galesic A, Balana A, Marotta NP, Lewis YE, Pratt MR. Levine PM, et al. Bioorg Med Chem. 2017 Sep 15;25(18):4977-4982. doi: 10.1016/j.bmc.2017.04.038. Epub 2017 Apr 29. Bioorg Med Chem. 2017. PMID: 28487126 Free PMC article.

8

The Sulfur-Linked Analogue of O-GlcNAc (S-GlcNAc) Is an Enzymatically Stable and Reasonable Structural Surrogate for O-GlcNAc at the Peptide and Protein Levels.

De Leon CA, Levine PM, Craven TW, Pratt MR. De Leon CA, et al. Among authors: levine pm. Biochemistry. 2017 Jul 11;56(27):3507-3517. doi: 10.1021/acs.biochem.7b00268. Epub 2017 Jun 30. Biochemistry. 2017. PMID: 28627871 Free PMC article.

9

Revolutionizing Our Understanding of Amyloidogenic Proteins by Cryo-Electron Microscopy.

Levine PM, Pratt MR. Levine PM, et al. Biochemistry. 2018 Feb 13;57(6):895-896. doi: 10.1021/acs.biochem.7b01084. Epub 2018 Jan 11. Biochemistry. 2018. PMID: 29323876 No abstract available.

10

α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease.

Levine PM, Galesic A, Balana AT, Mahul-Mellier AL, Navarro MX, De Leon CA, Lashuel HA, Pratt MR. Levine PM, et al. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1511-1519. doi: 10.1073/pnas.1808845116. Epub 2019 Jan 16. Proc Natl Acad Sci U S A. 2019. PMID: 30651314 Free PMC article.

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