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PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
Wickramasinghe NM, Sachs D, Shewale B, Gonzalez DM, Dhanan-Krishnan P, Torre D, LaMarca E, Raimo S, Dariolli R, Serasinghe MN, Mayourian J, Sebra R, Beaumont K, Iyengar S, French DL, Hansen A, Eschenhagen T, Chipuk JE, Sobie EA, Jacobs A, Akbarian S, Ischiropoulos H, Ma'ayan A, Houten SM, Costa K, Dubois NC. Wickramasinghe NM, et al. Among authors: serasinghe mn. Cell Stem Cell. 2022 Apr 7;29(4):559-576.e7. doi: 10.1016/j.stem.2022.02.011. Epub 2022 Mar 23. Cell Stem Cell. 2022. PMID: 35325615 Free PMC article.
Mitochondrial Fission in Human Diseases.
Serasinghe MN, Chipuk JE. Serasinghe MN, et al. Handb Exp Pharmacol. 2017;240:159-188. doi: 10.1007/164_2016_38. Handb Exp Pharmacol. 2017. PMID: 28040850 Free PMC article. Review.
MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network.
Elkholi R, Abraham-Enachescu I, Trotta AP, Rubio-Patiño C, Mohammed JN, Luna-Vargas MPA, Gelles JD, Kaminetsky JR, Serasinghe MN, Zou C, Ali S, McStay GP, Pfleger CM, Chipuk JE. Elkholi R, et al. Among authors: serasinghe mn. Mol Cell. 2019 May 2;74(3):452-465.e7. doi: 10.1016/j.molcel.2019.02.012. Epub 2019 Mar 14. Mol Cell. 2019. PMID: 30879903 Free PMC article.
Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.
Rimmelé P, Liang R, Bigarella CL, Kocabas F, Xie J, Serasinghe MN, Chipuk J, Sadek H, Zhang CC, Ghaffari S. Rimmelé P, et al. Among authors: serasinghe mn. EMBO Rep. 2015 Sep;16(9):1164-76. doi: 10.15252/embr.201439704. Epub 2015 Jul 24. EMBO Rep. 2015. PMID: 26209246 Free PMC article.
FBXW7 regulates a mitochondrial transcription program by modulating MITF.
Abbate F, Badal B, Mendelson K, Aydin IT, Serasinghe MN, Iqbal R, Mohammed JN, Solovyov A, Greenbaum BD, Chipuk JE, Celebi JT. Abbate F, et al. Among authors: serasinghe mn. Pigment Cell Melanoma Res. 2018 Sep;31(5):636-640. doi: 10.1111/pcmr.12704. Epub 2018 Apr 29. Pigment Cell Melanoma Res. 2018. PMID: 29665239 Free PMC article.
From zero to sixty: cell death signaling in the city that never sleeps.
Gelles JD, Elkholi R, Serasinghe MN, Luna-Vargas MP, Chipuk JE. Gelles JD, et al. Among authors: serasinghe mn. Oncogene. 2016 Mar 17;35(11):1457-60. doi: 10.1038/onc.2015.194. Epub 2015 Jul 6. Oncogene. 2016. PMID: 26148239 Free PMC article. No abstract available.
Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.
Renault TT, Floros KV, Elkholi R, Corrigan KA, Kushnareva Y, Wieder SY, Lindtner C, Serasinghe MN, Asciolla JJ, Buettner C, Newmeyer DD, Chipuk JE. Renault TT, et al. Among authors: serasinghe mn. Mol Cell. 2015 Jan 8;57(1):69-82. doi: 10.1016/j.molcel.2014.10.028. Epub 2014 Dec 4. Mol Cell. 2015. PMID: 25482509 Free PMC article.
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