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Genetic instability from a single S phase after whole-genome duplication.
Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, Goundiam O, Hochegger H, Piel M, Foijer F, Storchová Z, Basto R. Gemble S, et al. Among authors: storchova z. Nature. 2022 Apr;604(7904):146-151. doi: 10.1038/s41586-022-04578-4. Epub 2022 Mar 30. Nature. 2022. PMID: 35355016 Free PMC article.
The presence of extra chromosomes leads to genomic instability.
Passerini V, Ozeri-Galai E, de Pagter MS, Donnelly N, Schmalbrock S, Kloosterman WP, Kerem B, Storchová Z. Passerini V, et al. Among authors: storchova z. Nat Commun. 2016 Feb 15;7:10754. doi: 10.1038/ncomms10754. Nat Commun. 2016. PMID: 26876972 Free PMC article.
The diverse consequences of aneuploidy.
Chunduri NK, Storchová Z. Chunduri NK, et al. Among authors: storchova z. Nat Cell Biol. 2019 Jan;21(1):54-62. doi: 10.1038/s41556-018-0243-8. Epub 2019 Jan 2. Nat Cell Biol. 2019. PMID: 30602769 Review.
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.
Cohen-Sharir Y, McFarland JM, Abdusamad M, Marquis C, Bernhard SV, Kazachkova M, Tang H, Ippolito MR, Laue K, Zerbib J, Malaby HLH, Jones A, Stautmeister LM, Bockaj I, Wardenaar R, Lyons N, Nagaraja A, Bass AJ, Spierings DCJ, Foijer F, Beroukhim R, Santaguida S, Golub TR, Stumpff J, Storchová Z, Ben-David U. Cohen-Sharir Y, et al. Among authors: storchova z. Nature. 2021 Feb;590(7846):486-491. doi: 10.1038/s41586-020-03114-6. Epub 2021 Jan 27. Nature. 2021. PMID: 33505028 Free PMC article.
Systems approaches identify the consequences of monosomy in somatic human cells.
Chunduri NK, Menges P, Zhang X, Wieland A, Gotsmann VL, Mardin BR, Buccitelli C, Korbel JO, Willmund F, Kschischo M, Raeschle M, Storchova Z. Chunduri NK, et al. Among authors: storchova z. Nat Commun. 2021 Sep 22;12(1):5576. doi: 10.1038/s41467-021-25288-x. Nat Commun. 2021. PMID: 34552071 Free PMC article.
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling.
Bernhard SV, Seget-Trzensiok K, Kuffer C, Krastev DB, Stautmeister LM, Theis M, Keuper K, Boekenkamp JE, Kschischo M, Buchholz F, Storchova Z. Bernhard SV, et al. Among authors: storchova z. Cell Oncol (Dordr). 2022 Feb;45(1):103-119. doi: 10.1007/s13402-021-00654-5. Epub 2021 Dec 28. Cell Oncol (Dordr). 2022. PMID: 34962618 Free PMC article.
83 results