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Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients.
Nijstad AL, Tibben MM, Gebretensae A, Rosing H, de Vos-Kerkhof E, Zwaan CM, Huitema ADR, Beijnen JH. Nijstad AL, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 May 1;1171:122639. doi: 10.1016/j.jchromb.2021.122639. Epub 2021 Mar 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33756449 Free article.
Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.
Chu WY, Annink KV, Nijstad AL, Maiwald CA, Schroth M, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Franz AR, Dorlo TPC, Allegaert K, Huitema ADR; ALBINO Study Group. Chu WY, et al. Among authors: nijstad al. Clin Pharmacokinet. 2022 Feb;61(2):321-333. doi: 10.1007/s40262-021-01068-0. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617261 Free PMC article. Clinical Trial.
Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia.
Dekker L, Calkoen FG, Jiang Y, Blok H, Veldkamp SR, De Koning C, Spoon M, Admiraal R, Hoogerbrugge P, Vormoor B, Vormoor HJ, Visscher H, Bierings M, Van Der Vlugt M, Van Tinteren H, Nijstad AL, Huitema ADR, Van Der Elst KCM, Pieters R, Lindemans CA, Nierkens S. Dekker L, et al. Among authors: nijstad al. Blood Adv. 2022 Apr 12;6(7):1969-1976. doi: 10.1182/bloodadvances.2021006700. Blood Adv. 2022. PMID: 35134115 Free PMC article.
A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS.
van der Heijden LT, Gebretensae A, Thijssen B, van Andel L, Nijstad AL, Wang Y, Rosing H, Huitema ADR, Beijnen JH. van der Heijden LT, et al. Among authors: nijstad al. J Pharm Biomed Anal. 2022 Jun 5;215:114772. doi: 10.1016/j.jpba.2022.114772. Epub 2022 Apr 16. J Pharm Biomed Anal. 2022. PMID: 35462284
Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.
Nijstad AL, de Vos-Kerkhof E, Enters-Weijnen CF, van de Wetering MD, Tissing WJE, Tibben MM, Rosing H, Lalmohamed A, Huitema ADR, Zwaan CM. Nijstad AL, et al. Support Care Cancer. 2022 Dec;30(12):9991-9999. doi: 10.1007/s00520-022-07423-6. Epub 2022 Oct 26. Support Care Cancer. 2022. PMID: 36287279 Free PMC article.
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