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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: bluher m. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.
microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.
de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S. de Guia RM, et al. Among authors: bluher m. EMBO J. 2015 Feb 3;34(3):344-60. doi: 10.15252/embj.201490464. Epub 2014 Dec 15. EMBO J. 2015. PMID: 25510864 Free PMC article. Clinical Trial.
PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis.
Cheng YS, Seibert O, Klöting N, Dietrich A, Straßburger K, Fernández-Veledo S, Vendrell JJ, Zorzano A, Blüher M, Herzig S, Berriel Diaz M, Teleman AA. Cheng YS, et al. Among authors: bluher m. PLoS Genet. 2015 Oct 6;11(10):e1005561. doi: 10.1371/journal.pgen.1005561. eCollection 2015 Oct. PLoS Genet. 2015. PMID: 26440364 Free PMC article.
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
Gautheron J, Vucur M, Schneider AT, Severi I, Roderburg C, Roy S, Bartneck M, Schrammen P, Diaz MB, Ehling J, Gremse F, Heymann F, Koppe C, Lammers T, Kiessling F, Van Best N, Pabst O, Courtois G, Linkermann A, Krautwald S, Neumann UP, Tacke F, Trautwein C, Green DR, Longerich T, Frey N, Luedde M, Bluher M, Herzig S, Heikenwalder M, Luedde T. Gautheron J, et al. Among authors: bluher m. Nat Commun. 2016 Jun 21;7:11869. doi: 10.1038/ncomms11869. Nat Commun. 2016. PMID: 27323669 Free PMC article.
Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.
Ekim Üstünel B, Friedrich K, Maida A, Wang X, Krones-Herzig A, Seibert O, Sommerfeld A, Jones A, Sijmonsma TP, Sticht C, Gretz N, Fleming T, Nawroth PP, Stremmel W, Rose AJ, Berriel-Diaz M, Blüher M, Herzig S. Ekim Üstünel B, et al. Among authors: bluher m. Nat Commun. 2016 Nov 9;7:13267. doi: 10.1038/ncomms13267. Nat Commun. 2016. PMID: 27827363 Free PMC article.
Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation.
Weiner J, Rohde K, Krause K, Zieger K, Klöting N, Kralisch S, Kovacs P, Stumvoll M, Blüher M, Böttcher Y, Heiker JT. Weiner J, et al. Among authors: bluher m. Mol Metab. 2017 Mar 28;6(6):482-493. doi: 10.1016/j.molmet.2017.03.004. eCollection 2017 Jun. Mol Metab. 2017. PMID: 28580279 Free PMC article.
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype.
Haim Y, Blüher M, Konrad D, Goldstein N, Klöting N, Harman-Boehm I, Kirshtein B, Ginsberg D, Tarnovscki T, Gepner Y, Shai I, Rudich A. Haim Y, et al. Among authors: bluher m. Mol Metab. 2017 May 6;6(7):725-736. doi: 10.1016/j.molmet.2017.05.003. eCollection 2017 Jul. Mol Metab. 2017. PMID: 28702328 Free PMC article.
739 results