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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: morgenstern j. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J. Schmöhl F, et al. Among authors: morgenstern j. Cell Mol Life Sci. 2019 Nov;76(22):4551-4568. doi: 10.1007/s00018-019-03127-z. Epub 2019 May 9. Cell Mol Life Sci. 2019. PMID: 31073745 Free PMC article.
The combination of loss of glyoxalase1 and obesity results in hyperglycemia.
Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J. Lodd E, et al. Among authors: morgenstern j. JCI Insight. 2019 Jun 20;4(12):e126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20. JCI Insight. 2019. PMID: 31217350 Free PMC article.
333 results