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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: volk n. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan.
Mendler M, Riedinger C, Schlotterer A, Volk N, Fleming T, Herzig S, Nawroth PP, Morcos M. Mendler M, et al. Among authors: volk n. J Diabetes Complications. 2017 Feb;31(2):304-310. doi: 10.1016/j.jdiacomp.2016.09.014. Epub 2016 Oct 1. J Diabetes Complications. 2017. PMID: 27776915
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J. Schmöhl F, et al. Among authors: volk n. Cell Mol Life Sci. 2019 Nov;76(22):4551-4568. doi: 10.1007/s00018-019-03127-z. Epub 2019 May 9. Cell Mol Life Sci. 2019. PMID: 31073745 Free PMC article.
A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.
Weigand T, Colbatzky F, Pfeffer T, Garbade SF, Klingbeil K, Colbatzky F, Becker M, Zemva J, Bulkescher R, Schürfeld R, Thiel C, Volk N, Reuss D, Hoffmann GF, Freichel M, Hecker M, Poth T, Fleming T, Poschet G, Schmitt CP, Peters V. Weigand T, et al. Among authors: volk n. Int J Mol Sci. 2020 Jul 10;21(14):4887. doi: 10.3390/ijms21144887. Int J Mol Sci. 2020. PMID: 32664451 Free PMC article.
Regulation of Gluconeogenesis by Aldo-keto-reductase 1a1b in Zebrafish.
Li X, Schmöhl F, Qi H, Bennewitz K, Tabler CT, Poschet G, Hell R, Volk N, Poth T, Hausser I, Morgenstern J, Fleming T, Nawroth PP, Kroll J. Li X, et al. Among authors: volk n. iScience. 2020 Nov 3;23(12):101763. doi: 10.1016/j.isci.2020.101763. eCollection 2020 Dec 18. iScience. 2020. PMID: 33251496 Free PMC article.
Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations.
Qi H, Schmöhl F, Li X, Qian X, Tabler CT, Bennewitz K, Sticht C, Morgenstern J, Fleming T, Volk N, Hausser I, Heidenreich E, Hell R, Nawroth PP, Kroll J. Qi H, et al. Among authors: volk n. Adv Sci (Weinh). 2021 Sep;8(18):e2101281. doi: 10.1002/advs.202101281. Epub 2021 Jul 18. Adv Sci (Weinh). 2021. PMID: 34278746 Free PMC article.
51 results