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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: zeigerer a. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.
A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage.
Niopek K, Üstünel BE, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail AM, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes HP, Nawroth P, Fleming T, Conkright MD, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M. Niopek K, et al. Among authors: zeigerer a. Cell Rep. 2017 Aug 8;20(6):1422-1434. doi: 10.1016/j.celrep.2017.07.023. Cell Rep. 2017. PMID: 28793265 Free article.
Energy metabolism in cachexia.
Rohm M, Zeigerer A, Machado J, Herzig S. Rohm M, et al. Among authors: zeigerer a. EMBO Rep. 2019 Apr;20(4):e47258. doi: 10.15252/embr.201847258. Epub 2019 Mar 19. EMBO Rep. 2019. PMID: 30890538 Free PMC article. Review.
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
Seitz S, Kwon Y, Hartleben G, Jülg J, Sekar R, Krahmer N, Najafi B, Loft A, Gancheva S, Stemmer K, Feuchtinger A, Hrabe de Angelis M, Müller TD, Mann M, Blüher M, Roden M, Berriel Diaz M, Behrends C, Gilleron J, Herzig S, Zeigerer A. Seitz S, et al. Among authors: zeigerer a. Nat Metab. 2019 Oct;1(10):1009-1026. doi: 10.1038/s42255-019-0124-x. Epub 2019 Oct 14. Nat Metab. 2019. PMID: 32694843
Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.
Novikoff A, O'Brien SL, Bernecker M, Grandl G, Kleinert M, Knerr PJ, Stemmer K, Klingenspor M, Zeigerer A, DiMarchi R, Tschöp MH, Finan B, Calebiro D, Müller TD. Novikoff A, et al. Among authors: zeigerer a. Mol Metab. 2021 Jul;49:101181. doi: 10.1016/j.molmet.2021.101181. Epub 2021 Feb 6. Mol Metab. 2021. PMID: 33556643 Free PMC article.
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.
Hartleben G, Schorpp K, Kwon Y, Betz B, Tsokanos FF, Dantes Z, Schäfer A, Rothenaigner I, Monroy Kuhn JM, Morigny P, Mehr L, Lin S, Seitz S, Tokarz J, Artati A, Adamsky J, Plettenburg O, Lutter D, Irmler M, Beckers J, Reichert M, Hadian K, Zeigerer A, Herzig S, Berriel Diaz M. Hartleben G, et al. Among authors: zeigerer a. EMBO Mol Med. 2021 Apr 9;13(4):e12461. doi: 10.15252/emmm.202012461. Epub 2021 Mar 5. EMBO Mol Med. 2021. PMID: 33665961 Free PMC article.
Glucagon's Metabolic Action in Health and Disease.
Zeigerer A, Sekar R, Kleinert M, Nason S, Habegger KM, Müller TD. Zeigerer A, et al. Compr Physiol. 2021 Apr 1;11(2):1759-1783. doi: 10.1002/cphy.c200013. Compr Physiol. 2021. PMID: 33792899 Free PMC article.
NAFLD - A rising metabolic disease.
Zeigerer A. Zeigerer A. Mol Metab. 2021 Aug;50:101274. doi: 10.1016/j.molmet.2021.101274. Epub 2021 Jul 2. Mol Metab. 2021. PMID: 34229990 Free PMC article. No abstract available.
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S. Loft A, et al. Among authors: zeigerer a. Cell Metab. 2022 Mar 1;34(3):473-486.e9. doi: 10.1016/j.cmet.2022.01.004. Epub 2022 Feb 3. Cell Metab. 2022. PMID: 35120589 Free article.
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
Sekar R, Motzler K, Kwon Y, Novikoff A, Jülg J, Najafi B, Wang S, Warnke AL, Seitz S, Hass D, Gancheva S, Kahl S, Yang B, Finan B, Schwarz K, Okun JG, Roden M, Blüher M, Müller TD, Krahmer N, Behrends C, Plettenburg O, Miaczynska M, Herzig S, Zeigerer A. Sekar R, et al. Among authors: zeigerer a. Cell Metab. 2022 Nov 1;34(11):1824-1842.e9. doi: 10.1016/j.cmet.2022.09.022. Epub 2022 Oct 14. Cell Metab. 2022. PMID: 36243006 Free article.
40 results