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Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents.
Berghausen EM, Janssen W, Vantler M, Gnatzy-Feik LL, Krause M, Behringer A, Joseph C, Zierden M, Freyhaus HT, Klinke A, Baldus S, Alcazar MA, Savai R, Pullamsetti SS, Wong DW, Boor P, Zhao JJ, Schermuly RT, Rosenkranz S. Berghausen EM, et al. Among authors: gnatzy feik ll. J Clin Invest. 2021 Oct 1;131(19):e136939. doi: 10.1172/JCI136939. J Clin Invest. 2021. PMID: 34596056 Free PMC article.
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress.
Müller M, Bischof C, Kapries T, Wollnitza S, Liechty C, Geißen S, Schubert T, Opacic D, Gerçek M, Fortmeier V, Dumitrescu D, Schlomann U, Sydykov A, Petrovic A, Gnatzy-Feik L, Milting H, Schermuly RT, Friedrichs K, Rudolph V, Klinke A. Müller M, et al. Among authors: gnatzy feik l. JACC Basic Transl Sci. 2022 Jul 6;7(7):658-677. doi: 10.1016/j.jacbts.2022.02.018. eCollection 2022 Jul. JACC Basic Transl Sci. 2022. PMID: 35958691 Free PMC article.