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Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells.
Papageorgiou AP, Swinnen M, Vanhoutte D, VandenDriessche T, Chuah M, Lindner D, Verhesen W, de Vries B, D'hooge J, Lutgens E, Westermann D, Carmeliet P, Heymans S. Papageorgiou AP, et al. Among authors: heymans s. Cardiovasc Res. 2012 Apr 1;94(1):115-24. doi: 10.1093/cvr/cvs077. Epub 2012 Feb 2. Cardiovasc Res. 2012. PMID: 22308237
MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis.
Corsten MF, Papageorgiou A, Verhesen W, Carai P, Lindow M, Obad S, Summer G, Coort SL, Hazebroek M, van Leeuwen R, Gijbels MJ, Wijnands E, Biessen EA, De Winther MP, Stassen FR, Carmeliet P, Kauppinen S, Schroen B, Heymans S. Corsten MF, et al. Among authors: heymans s. Circ Res. 2012 Aug 3;111(4):415-25. doi: 10.1161/CIRCRESAHA.112.267443. Epub 2012 Jun 19. Circ Res. 2012. PMID: 22715471
STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy.
Camporeale A, Marino F, Papageorgiou A, Carai P, Fornero S, Fletcher S, Page BD, Gunning P, Forni M, Chiarle R, Morello M, Jensen O, Levi R, Heymans S, Poli V. Camporeale A, et al. Among authors: heymans s. EMBO Mol Med. 2013 Apr;5(4):572-90. doi: 10.1002/emmm.201201876. Epub 2013 Mar 5. EMBO Mol Med. 2013. PMID: 23460527 Free PMC article.
Macrophage microRNA-155 promotes cardiac hypertrophy and failure.
Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, de Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Heymans S, et al. Circulation. 2013 Sep 24;128(13):1420-32. doi: 10.1161/CIRCULATIONAHA.112.001357. Epub 2013 Aug 16. Circulation. 2013. PMID: 23956210
341 results