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Cell-Selective Adeno-Associated Virus-Mediated SCN1A Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates.
Tanenhaus A, Stowe T, Young A, McLaughlin J, Aeran R, Lin IW, Li J, Hosur R, Chen M, Leedy J, Chou T, Pillay S, Vila MC, Kearney JA, Moorhead M, Belle A, Tagliatela S. Tanenhaus A, et al. Among authors: moorhead m. Hum Gene Ther. 2022 Jun;33(11-12):579-597. doi: 10.1089/hum.2022.037. Hum Gene Ther. 2022. PMID: 35435735 Free PMC article.
Optimal genotype determination in highly multiplexed SNP data.
Moorhead M, Hardenbol P, Siddiqui F, Falkowski M, Bruckner C, Ireland J, Jones HB, Jain M, Willis TD, Faham M. Moorhead M, et al. Eur J Hum Genet. 2006 Feb;14(2):207-15. doi: 10.1038/sj.ejhg.5201528. Eur J Hum Genet. 2006. PMID: 16306880
SNP discovery in pooled samples with mismatch repair detection.
Fakhrai-Rad H, Zheng J, Willis TD, Wong K, Suyenaga K, Moorhead M, Eberle J, Thorstenson YR, Jones T, Davis RW, Namsaraev E, Faham M. Fakhrai-Rad H, et al. Among authors: moorhead m. Genome Res. 2004 Jul;14(7):1404-12. doi: 10.1101/gr.2373904. Genome Res. 2004. PMID: 15231755 Free PMC article.
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay.
Hardenbol P, Yu F, Belmont J, Mackenzie J, Bruckner C, Brundage T, Boudreau A, Chow S, Eberle J, Erbilgin A, Falkowski M, Fitzgerald R, Ghose S, Iartchouk O, Jain M, Karlin-Neumann G, Lu X, Miao X, Moore B, Moorhead M, Namsaraev E, Pasternak S, Prakash E, Tran K, Wang Z, Jones HB, Davis RW, Willis TD, Gibbs RA. Hardenbol P, et al. Among authors: moorhead m. Genome Res. 2005 Feb;15(2):269-75. doi: 10.1101/gr.3185605. Genome Res. 2005. PMID: 15687290 Free PMC article.
Allele quantification using molecular inversion probes (MIP).
Wang Y, Moorhead M, Karlin-Neumann G, Falkowski M, Chen C, Siddiqui F, Davis RW, Willis TD, Faham M. Wang Y, et al. Among authors: moorhead m. Nucleic Acids Res. 2005 Nov 28;33(21):e183. doi: 10.1093/nar/gni177. Nucleic Acids Res. 2005. PMID: 16314297 Free PMC article.
Population structure, differential bias and genomic control in a large-scale, case-control association study.
Clayton DG, Walker NM, Smyth DJ, Pask R, Cooper JD, Maier LM, Smink LJ, Lam AC, Ovington NR, Stevens HE, Nutland S, Howson JM, Faham M, Moorhead M, Jones HB, Falkowski M, Hardenbol P, Willis TD, Todd JA. Clayton DG, et al. Among authors: moorhead m. Nat Genet. 2005 Nov;37(11):1243-6. doi: 10.1038/ng1653. Epub 2005 Oct 9. Nat Genet. 2005. PMID: 16228001
High-throughput, high-accuracy array-based resequencing.
Zheng J, Moorhead M, Weng L, Siddiqui F, Carlton VE, Ireland JS, Lee L, Peterson J, Wilkins J, Lin S, Kan Z, Seshagiri S, Davis RW, Faham M. Zheng J, et al. Among authors: moorhead m. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6712-7. doi: 10.1073/pnas.0901902106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342489 Free PMC article.
High-throughput method for analyzing methylation of CpGs in targeted genomic regions.
Nautiyal S, Carlton VE, Lu Y, Ireland JS, Flaucher D, Moorhead M, Gray JW, Spellman P, Mindrinos M, Berg P, Faham M. Nautiyal S, et al. Among authors: moorhead m. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12587-92. doi: 10.1073/pnas.1005173107. Epub 2010 Jun 23. Proc Natl Acad Sci U S A. 2010. PMID: 20616066 Free PMC article.
Multiplexed variation scanning for 1,000 amplicons in hundreds of patients using mismatch repair detection (MRD) on tag arrays.
Faham M, Zheng J, Moorhead M, Fakhrai-Rad H, Namsaraev E, Wong K, Wang Z, Chow SG, Lee L, Suyenaga K, Reichert J, Boudreau A, Eberle J, Bruckner C, Jain M, Karlin-Neumann G, Jones HB, Willis TD, Buxbaum JD, Davis RW. Faham M, et al. Among authors: moorhead m. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14717-22. doi: 10.1073/pnas.0506677102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203980 Free PMC article.
39 results