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A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors.
Young G, Liesner R, Chang T, Sidonio R, Oldenburg J, Jiménez-Yuste V, Mahlangu J, Kruse-Jarres R, Wang M, Uguen M, Doral MY, Wright LY, Schmitt C, Levy GG, Shima M, Mancuso ME. Young G, et al. Among authors: wang m. Blood. 2019 Dec 12;134(24):2127-2138. doi: 10.1182/blood.2019001869. Blood. 2019. PMID: 31697801 Free PMC article. Clinical Trial.
Optimal trough levels in haemophilia B: Raising expectations.
Walsh C, Coppens M, Escobar M, Wang M. Walsh C, et al. Among authors: wang m. Haemophilia. 2020 Nov;26(6):e334-e336. doi: 10.1111/hae.14098. Epub 2020 Aug 25. Haemophilia. 2020. PMID: 32842166 Free PMC article. No abstract available.
Real-world data demonstrate improved bleed control and extended dosing intervals for patients with haemophilia B after switching to recombinant factor IX Fc fusion protein (rFIXFc) for up to 5 years.
Shapiro A, Chaudhury A, Wang M, Escobar M, Tsao E, Barnowski C, Feng J, Jain N, Quon DV. Shapiro A, et al. Among authors: wang m. Haemophilia. 2020 Nov;26(6):975-983. doi: 10.1111/hae.14152. Epub 2020 Oct 4. Haemophilia. 2020. PMID: 33012060 Free PMC article.
PERSEPT 3: A phase 3 clinical trial to evaluate the haemostatic efficacy of eptacog beta (recombinant human FVIIa) in perioperative care in subjects with haemophilia A or B with inhibitors.
Escobar M, Luck J, Averianov Y, Ducore J, Fernández MFL, Giermasz A, Hart DP, Journeycake J, Kessler C, Leissinger C, Mahlangu J, Martinez LV, Miesbach W, Mitha IH, Quon D, Reding MT, Schved JF, Stasyshyn O, Vilchevska KV, Wang M, Windyga J, Alexander WA, Al-Sabbagh A, Bonzo D, Mitchell IS, Wilkinson TA, Hermans C. Escobar M, et al. Among authors: wang m. Haemophilia. 2021 Nov;27(6):911-920. doi: 10.1111/hae.14418. Epub 2021 Oct 6. Haemophilia. 2021. PMID: 34614267 Free PMC article. Clinical Trial.
The safety of activated eptacog beta in the management of bleeding episodes and perioperative haemostasis in adult and paediatric haemophilia patients with inhibitors.
Escobar M, Castaman G, Boix SB, Callaghan M, de Moerloose P, Ducore J, Hermans C, Journeycake J, Leissinger C, Luck J, Mahlangu J, Miesbach W, Mitha IH, Négrier C, Quon D, Recht M, Schved JF, Shapiro AD, Sidonio R Jr, Srivastava A, Stasyshyn O, Vilchevska KV, Wang M, Young G, Alexander WA, Al-Sabbagh A, Bonzo D, Macie C, Wilkinson TA, Kessler C. Escobar M, et al. Among authors: wang m. Haemophilia. 2021 Nov;27(6):921-931. doi: 10.1111/hae.14419. Epub 2021 Oct 11. Haemophilia. 2021. PMID: 34636112 Free PMC article. Clinical Trial.
Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational study.
Kleiboer B, Layer MA, Cafuir LA, Cuker A, Escobar M, Eyster ME, Kraut E, Leavitt AD, Lentz SR, Quon D, Ragni MV, Thornhill D, Wang M, Key NS, Buckner TW. Kleiboer B, et al. Among authors: wang m. J Thromb Haemost. 2022 Apr;20(4):857-865. doi: 10.1111/jth.15654. Epub 2022 Feb 8. J Thromb Haemost. 2022. PMID: 35080347 Free PMC article.
Eptacog beta efficacy and safety in the treatment and control of bleeding in paediatric subjects (<12 years) with haemophilia A or B with inhibitors.
Pipe SW, Hermans C, Chitlur M, Carcao M, Castaman G, Davis JA, Ducore J, Dunn AL, Escobar M, Journeycake J, Khan O, Mahlangu J, Meeks SL, Mitha IH, Négrier C, Nowak-Göttl U, Recht M, Chrisentery-Singleton T, Stasyshyn O, Vilchevska KV, Martinez LV, Wang M, Windyga J, Young G, Alexander WA, Bonzo D, Macie C, Mitchell IS, Sauty E, Wilkinson TA, Shapiro AD. Pipe SW, et al. Among authors: wang m. Haemophilia. 2022 Jul;28(4):548-556. doi: 10.1111/hae.14563. Epub 2022 Apr 27. Haemophilia. 2022. PMID: 35475308 Free PMC article. Clinical Trial.
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