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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation.
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Roh JW, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Di Germanio C, Rizvi N, Liu H, Ma ZM, Stone M, Simmons G, Dumont LJ, Allen AM, Lockwood S, Pollard RE, Ramiro de Assis R, Yee JL, Nham PB, Ardeshir A, Deere JD, Jain A, Felgner PL, Coffey LL, Iyer SS, Hartigan-O'Connor DJ, Busch MP, Reader JR. Van Rompay KKA, et al. Among authors: di germanio c. PLoS Pathog. 2022 Apr 20;18(4):e1009925. doi: 10.1371/journal.ppat.1009925. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35443018 Free PMC article.
Selecting COVID-19 convalescent plasma for neutralizing antibody potency using a high-capacity SARS-CoV-2 antibody assay.
Goodhue Meyer E, Simmons G, Grebe E, Gannett M, Franz S, Darst O, Di Germanio C, Stone M, Contestable P, Prichard A, Reik R, Vassallo R, Young P, Busch MP, Williamson P, Dumont LJ. Goodhue Meyer E, et al. Among authors: di germanio c. Transfusion. 2021 Apr;61(4):1160-1170. doi: 10.1111/trf.16321. Epub 2021 Feb 18. Transfusion. 2021. PMID: 33554362 Free PMC article.
Minipool testing for SARS-CoV-2 RNA in United States blood donors.
Bakkour S, Saá P, Groves JA, Montalvo L, Di Germanio C, Best SM, Grebe E, Livezey K, Linnen JM, Strauss D, Kessler D, Bonn M, Green V, Williamson P, Kleinman S, Stramer SL, Stone M, Busch MP; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P). Bakkour S, et al. Among authors: di germanio c. Transfusion. 2021 Aug;61(8):2384-2391. doi: 10.1111/trf.16511. Epub 2021 May 27. Transfusion. 2021. PMID: 34046906
Use of US Blood Donors for National Serosurveillance of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies: Basis for an Expanded National Donor Serosurveillance Program.
Stone M, Di Germanio C, Wright DJ, Sulaeman H, Dave H, Fink RV, Notari EP, Green V, Strauss D, Kessler D, Destree M, Saa P, Williamson PC, Simmons G, Stramer SL, Opsomer J, Jones JM, Kleinman S, Busch MP; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P). Stone M, et al. Among authors: di germanio c. Clin Infect Dis. 2022 Mar 9;74(5):871-881. doi: 10.1093/cid/ciab537. Clin Infect Dis. 2022. PMID: 34111244 Free PMC article.
SARS-CoV-2 antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance.
Di Germanio C, Simmons G, Kelly K, Martinelli R, Darst O, Azimpouran M, Stone M, Hazegh K, Grebe E, Zhang S, Ma P, Orzechowski M, Gomez JE, Livny J, Hung DT, Vassallo R, Busch MP, Dumont LJ. Di Germanio C, et al. Transfusion. 2021 Sep;61(9):2677-2687. doi: 10.1111/trf.16555. Epub 2021 Jun 20. Transfusion. 2021. PMID: 34121205 Free PMC article.
SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.
Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J Jr, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. Peluso MJ, et al. Sci Adv. 2021 Jul 30;7(31):eabh3409. doi: 10.1126/sciadv.abh3409. Print 2021 Jul. Sci Adv. 2021. PMID: 34330709 Free PMC article.
Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019.
Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF. Bainbridge ED, et al. Among authors: di germanio c. Open Forum Infect Dis. 2021 Jul 16;8(8):ofab385. doi: 10.1093/ofid/ofab385. eCollection 2021 Aug. Open Forum Infect Dis. 2021. PMID: 34405093 Free PMC article.
Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment.
Chen L, Zody MC, Di Germanio C, Martinelli R, Mediavilla JR, Cunningham MH, Composto K, Chow KF, Kordalewska M, Corvelo A, Oschwald DM, Fennessey S, Zetkulic M, Dar S, Kramer Y, Mathema B, Germer S, Stone M, Simmons G, Busch MP, Maniatis T, Perlin DS, Kreiswirth BN. Chen L, et al. Among authors: di germanio c. mSphere. 2021 Aug 25;6(4):e0048021. doi: 10.1128/mSphere.00480-21. Epub 2021 Aug 25. mSphere. 2021. PMID: 34431691 Free PMC article.
Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021.
Jones JM, Stone M, Sulaeman H, Fink RV, Dave H, Levy ME, Di Germanio C, Green V, Notari E, Saa P, Biggerstaff BJ, Strauss D, Kessler D, Vassallo R, Reik R, Rossmann S, Destree M, Nguyen KA, Sayers M, Lough C, Bougie DW, Ritter M, Latoni G, Weales B, Sime S, Gorlin J, Brown NE, Gould CV, Berney K, Benoit TJ, Miller MJ, Freeman D, Kartik D, Fry AM, Azziz-Baumgartner E, Hall AJ, MacNeil A, Gundlapalli AV, Basavaraju SV, Gerber SI, Patton ME, Custer B, Williamson P, Simmons G, Thornburg NJ, Kleinman S, Stramer SL, Opsomer J, Busch MP. Jones JM, et al. Among authors: di germanio c. JAMA. 2021 Oct 12;326(14):1400-1409. doi: 10.1001/jama.2021.15161. JAMA. 2021. PMID: 34473201 Free PMC article.
56 results